edited by Seetharaman Vaidyanathan, George G. Harrigan, Royston Goodacre.
New York :
Springer,
2005.
1 online resource (xix, 390 pages) :
illustrations
Includes bibliographical references and index.
Introduction / Seetharaman Vaidyanathan, George G. Harrigan and Royston Goodacre -- Towards integrative functional genomics using yeast as a reference model / Juan I. Castrillo and Stephen G. Oliver -- Metabolomics for the assessment of functional diversity and quality traits in plants / Robert D. Hall [and others] -- Metabolomics: a new approach towards identifying biomarkers and therapeutic targets in cns disorders / Rima Kaddurah-Daouk [and others] -- Compaative metabolome profiling using two dimensional thin layer chromatography (2DTLC) / Thomas Ferenci and Ram Maharjan -- Capillary electrophoresis and its application in metabolome analysis / Li Jia and Shigeru Terabe -- Metabolite profiling with GC-MS and LC-MS / Ralf Looser, Arno J. Krotzky, Richard N. Trethewey -- The application of electrochemistry to metabolic profiling / David F. Meyer, Paul H. Gamache and Ian N. Acworth -- Differential metabolic profiling for biomarker discovery / Haihong Zhou, Aaron B. Kantor and Christopher H. Becker -- NMR-based metabonomics in toxicology research / Laura K. Schnackenberg, Richard D. Beger, and Yvonne P. Dragan -- Methodological issues and experimental design considerations in metabolic profile-based classifications / Bruce S. Kristal [and others] -- Modelling of fungal metabolism / Helga David and Jens Nielsen -- Detailed kinetic models using metabolomics data sets / Jacky L. Snoep, Johann M. Rohwer -- Metabolic networks / Eivind Almaas, Zoltán N. Oltvai and Albert-László Barabási -- Metabolic networks from a systems perspective / Wolfran Weckwerth, Ralf Steuer -- Parallel metabolite and trascript profiling / Alisdair R. Fernie, Ewa Urbanczyk-Wochniak and Lothar Willmitzer -- Fluxome profiling in microbes / Nicola Zamboni and Uwe Sauer -- Targeted drug design and metabolic pathway flux / László G. Boros and Wai-Nang Paul Lee -- Metabonomics in the pharmaceutical industry / Eva M. Lenz, Rebecca Williams and Ian D. Wilson -- How lipidomic approaches will benefit the pharmaceutical industry / Alvin Berger -- Metabolites and fungal virulence / Edward M. Driggers and Axel A. Brakhage.
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"Metabolome analyses is now recognized as a crucial component of functional genomic and systems biology investigations. Innovative approaches to the study of metabolic regulation in microbial, plant and animal systems are increasingly facilitating the emergence of systems approaches in biology. Metabolome Analyses: Strategies for Systems Biology highlights analytical and bioinformatics strategies now available for investigating metabolic networks in microbial, plant and animal systems." "The contributing authors are world leaders in this field and they present an unambiguous case for pursuing metabolome analysis as a means to attain a systems level understanding of complex biological systems."--Jacket.