Cytochrome P450 : nature's most versatile biological catalyst / Minor J. Coon -- Cytochrome P450 activation of arylamines and heterocyclic amines / Donghak Kim and F. Peter Guengerich -- Glutathione transferases / John D. Hayes, Jack U. Flanagan, and Ian R. Jowsey -- Pleiotropic effects of satins / James K. Liao and Ulrich Laufs -- Fat cells : afferent and efferent messages define new approaches to treat obesity / Max Lafontan -- Formation and toxity of anesthetic degradation products / M.W. Anders -- The role of metabolic activation in drug-induced hepatotoxicity / B. Kevin Park [and others] -- Natural health products and drug disposition / Brian C. Foster, J. Thor Arnason, and Colin J. Briggs -- Biomarkers in psychotropic drug development : integration of data across multiple domains / Peter R. Bieck and William Z. Potter -- Neonicotinoid insecticide toxicology : mechanisms of selective action / Motohiro Tomizawa and John E. Casida -- Glyceraldehyde-3-phosphate dehydrogenase, apoptosis, and neurodegenerative diseases / De-Maw Chuang, Christopher Hough and Vladimir V. Sentorov -- Non-Michaelis-Menton kinetics in cytochrome P450-catalyzed reactions / William M. Atkins.
Epoxide hydrolases : mechanisms, inhibitor designs, and biological roles / Christophe Morisseau and Bruce D. Hammock -- Nitroxyl (HNO) : chemistry, biochemistry, and pharmacology / Jan M. Fukuto [and others] -- Tyrosine kinase inhibitors and the dawn of molecular cancer therapeutics / Raoul Tibes, Jonathan Trent, and Razelle Korzrock -- Actions of adenosine at its receptors in the CNS : insights from knockouts and drugs / Bertil B. Fredholm [and others] -- Regulation and inhibition of arachidonic acid (omega)-hydroxylases and 20-HETE formation / Deanna L. Kroetz and Fengyun Xu --Cytochrome P450 ubiquitination : branding for the proteolytic slaughter? / Marie Almira Correia, Sheila Sadeghi, and Eduardo Mundo-Paredes -- Proteasome inhibition in multiple myeloma : therapeutic implication / Dharminder Chauhan, Teru Hideshima, and Kenneth C. Anderson -- Clinical and toxicological relevance of CYP2C9 : drug-drug interactions and pharmacogenetics / Allan E. Rettie and Jeffrey P. Jones -- Clinical development of histone deacetylase inhibitors / Daryl C. Drummond [and others] -- The magic bullets and tuberculosis drug targets / Ying Zhang.
Molecular mechanisms of resistance in antimalarial chemotherapy : the unmet challenge / Ravit Arav-Boger and Theresa A. Shapiro 00 Signaling networks in living cells / Michael A. White and Richard G.W. Anderson -- Hepatic fibrosis : molecular mechanisms and drug targets / Sophie Lotersztajn [and others] -- Aberrant DNA methylation as a cancer-inducing mechanism / Manel Esteller -- The cardiac fibroblast : therapeutic target in myocardial remodeling and failure / R. Dale Brown [and others] -- Evaluation of drug-drug interaction in the hepatobiliary and renal transport of drugs / Yoshihisa Shitara, Hitoshi Sato, and Yuichi Sugiyama -- Dual specificity protein phosphates : therapeutic targets for cancer and Alzheimer's disease / Alexander P. Ducruet [and others].