The global burden of chronic obstructive pulmonary disease. Definition of chronic obstructive pulmonary disease / N.B. Pride. COPD: worldwide prevalence / A. Sonia Buist. Worldwide mortality for COPD / Jean-François Muir and Antoine Cuvelier. Risk factors for the development of COPD / Scott T. Weiss and Edwin K. Silverman. Risk factors for the progression of COPD / Huib A.M. Kerstjens and Dirkje S. Postma. Socioeconomic burden of COPD / Sean D. Sullivan, Todd A. Lee, and Sarika Ogale -- Pathogenic mechanisms in chronic obstructive pulmonary disease. Pathology of COPD / James C. Hogg. Inflammatory mechanisms / Robert A. Stockley. Defective repair in COPD: the American hypothesis / Stephen Rennard. Proteinases in COPD / Steven D. Shapiro. Oxidative stress and COPD / William W. MacNee and Irfan Rahman. Pathogenesis of infections in COPD patients / Muriel van Schilfgaarde [and others] Extrapulmonary effects of COPD / Nicholas J. Gross -- Long-term intervention strategies. Smoking cessation / Philip Tønnesen. Anticholinergics / Michael Brunson and William C. Bailey. Long-acting beta-adrenoreceptor agonists for the treatment of COPD / Dirkje S. Postma and Klaus F. Rabe. The role of glucocorticosteroids in the management of COPD / Romain Pauwels. Antibiotics in COPD / Nikolaos Siafakas, Eleni Tzortzaki and M. Tsoumakidou. Long-term intervention studies: [alpha]1-antitrypsin substitution / Robert A. Stockley. Surgery and transplantation for COPD / John R. Pepper. New therapies for COPD / Peter J. Barnes.
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"Reviewing current strategies and methods to treat and manage patients suffering with ventilatory dysfunction, this reference provides a critical overview of the epidemiology, pathophysiology, diagnosis, and outcomes of COPD - describing techniques to prevent and reduce the development of symptoms, improve patient quality of life, and slow the progression of disease."--Jacket.