edited by Allan Gaw, Christopher J. Packard, James Shepherd.
2nd ed.
Independence, KY :
Distributed in the USA by Taylor & Francis,
2004.
viii, 262 pages :
illustrations
Includes bibliographical references and index.
Hyperlipidaemia as a risk factor for vascular heart disease / Allan Gaw -- 2. Lipid control in the pre-statin era / William B. Kannel and Peter W.F. Wilson -- 3. The discovery and development of the statins / Akira Endo -- 4. Comparative chemistry, pharmacology and mechanism of action of the statins / Allan Gaw and Christopher J. Packard -- 5. Ancillary benefits of the statins / Brendan M. Buckley -- 6. Angiographic and IVUS techniques evaluating progression and regression of coronary atherosclerosis : statin intervention trials in perspective / Philippine Kiès, Albert V.G. Bruschke and J. Wouter Jukema -- 7. The Scandinavian Simvastatin survival study (4S) / Ole Faergeman -- 8. Primary prevention of coronary heart disease with statins / James Shepherd -- 9. The CARE trial : the effect of pravastatin on coronary events after myocardial infarction in patients with average cholesterol levels / J. Wayne Warnica -- 10. The LIPID study : results and implications for clinical practice / Andrew M. Tonkin, on behalf of the LIPID study group -- 11. Mega-trials : the prospective Pravastatin pooling project (PPP) and the heart protection study (HPS) / Robert P. Byington and Curt D. Furberg -- 12. The prospective study of Pravastatin in the elderly at risk (PROSPER) / James Shepherd [and others] -- 13. Combination therapy with statins / Gilbert R. Thompson -- 14. Guidelines for clinical use of the statins / Christopher J. Packard -- 15. The cost-effectiveness of statin use / J. Jaime Caro and Krista F. Huybrechts -- 16. Unanswered questions about the use of statins / Mehmet Cilingiroglu and Christie M. Ballantyne -- 17. Statin therapy for the 21st century / James Shepherd.