عنوان

Biological sequence analysis :

0511336438

0511337086

0511648715

051179049X

9780511336430

9780511337086

9780511648717

9780511790492

0521620414

0521629713

9780521620413

9780521629713

b737189

Biological sequence analysis :

[Book]

probabilistic models of proteins and nucleic acids /

Richard Durbin, Sean R. Eddy, Anders Krogh, Graeme Mitchison.

New York :

Cambridge University Press,

1998.

©1998

1 online resource (xi, 356 pages) :

illustrations

Includes bibliographical references (pages 326-344) and indexes.

Introduction -- Pairwise alignment -- Markov chains and hidden Markov models -- Pairwise alignment using HMMs -- Profile HMMs for sequence families -- Multiple sequence alignment methods -- Building phylogenetic trees -- Probabilistic approaches to phylogeny -- Transformational grammars -- RNA structure analysis -- Background on probability.

0

Presents up-to-date computer methods for analysing DNA, RNA and protein sequences.

Probabilistic models are becoming increasingly important in analysing the huge amount of data being produced by large-scale DNA-sequencing efforts such as the Human Genome Project. For example, hidden Markov models are used for analysing biological sequences, linguistic-grammar-based probabilistic models for identifying RNA secondary structure, and probabilistic evolutionary models for inferring phylogenies of sequences from different organisms. This book gives a unified, up-to-date and self-contained account, with a Bayesian slant, of such methods, and more generally to probabilistic methods of sequence analysis. Written by an interdisciplinary team of authors, it aims to be accessible to molecular biologists, computer scientists, and mathematicians with no formal knowledge of the other fields, and at the same time present the state-of-the-art in this new and highly important field.

Biological sequence analysis.

9780521629713

Amino acid sequence-- Data processing.

Amino acid sequence-- Statistical methods.

Markov processes.

Nucleotide sequence-- Data processing.

Nucleotide sequence-- Statistical methods.

Numerical analysis.

Probabilities.

Amino Acid Sequence.

Base Sequence.

Probability.

Sequence Analysis-- methods.

Analyse numérique.

Probabilités.

Séquence des acides aminés-- Méthodes statistiques.

Séquence nucléotidique-- Méthodes statistiques.

Amino acid sequence-- Data processing.

Amino acid sequence-- Statistical methods.

Amino acids.

Aminosyresekvenser-- Statistiske metoder.

Bioinformatics.

Bioinformatique.

Génétique moléculaire.

Markov processes.

Nucleic acids.

Nucleotide sequence-- Data processing.

Nucleotide sequence-- Statistical methods.

Nucleotide sequence.

Nukleotidsekvenser-- Statistiske metoder.

Numerical analysis.

Phylogeny.

Probabilités.

Probabilities.

Proteins.

SCIENCE-- Life Sciences-- Genetics & Genomics.

Séquençage des acides aminés-- Méthodes statistiques.

Séquençage des acides nucléiques-- Logiciels.

Séquence nucléotidique-- Méthodes statistiques.

Statistical methods.

SCI-- 029000

577.112.5:519.2

577.212.3:519.2

Durbin, Richard

20201203215540.0

pn

[Book]

Y