John B. West, Robert B. Schoene, James S. Milledge.
4th ed.
London :
Hodder Arnold,
2007.
viii, 484 pages :
illustrations ;
25 cm
Includes bibliographical references (pages 399-469) and index.
History -- The atmosphere -- Geography and the human response to altitude -- Altitude acclimatization and deterioration -- Ventilatory response to hypoxia and carbon dioxide -- Pulmonary gas exchange -- Cardiovascular system -- Hematology -- Blood-gas transport and acid-base balance -- Peripheral tissues -- Exercise -- Limiting factors at extreme altitude -- Sleep -- Nutrition, metabolism and intestinal function -- Endocrine and renal systems at altitude -- Central nervous system -- High altitude populations -- Acute mountain sickness -- High altitude cerebral edema -- High altitude pulmonary edema -- Chronic mountain sickness and high altitude pulmonary hypertension -- Other altitude-related conditions : neurovascular disorders, eye conditions, altitude cough, anesthesia at altitude -- The physiology and pathology of heat and cold -- Pre-existing medical conditions at altitude -- Women at altitude -- Extremes of age at altitude : children and the elderly -- Commuting to high altitude for commercial and other activities -- Athletes and altitude -- Clinical lessons from high altitude -- Practicalities of field studies.
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More than half a century has passed since man first stood on the summit of Mount Everest, and the story of man's attempts to climb higher and higher unaided is one of the more colorful and exciting in medicine and physiology. The past few decades have seen an explosion in interest in mountain pursuits in general, as increasing numbers of people take to the mountains for day trips and on longer excursions. As a result, doctors face ever-expanding challenges in dealing with the changes in human physiology and particular medical conditions that arise from exposure to altitude.