Oxidative stress in applied basic research and clinical practice
Includes bibliographical references and index.
Preface; Contents; Contributors; 1 The Evolving Concept of Oxidative Stress; 2 Mechanisms of Redox Signaling in Cardiovascular Disease; 3 Reactive Oxygen and Nitrogen Species in Cardiovascular Differentiation of Stem Cells; 4 Reactive Oxygen Species (ROS) and the Sensory Neurovascular Component; 5 Mitochondrial Reactive Oxygen Species in Myocardial Pre- and Postconditioning; 6 Coenzyme Q9/Q10 and the Healthy Heart; 7 Oxidative and Proteolytic Stress in Homocysteine-Associated Cardiovascular Diseases; 8 Functional Studies of NADPH Oxidases in Human Vasculature.
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This collection of articles on oxidative stress in clinical practice surveys essential current research in what is a rapidly evolving field. As well as giving the reader a mechanistic overview of how oxidative stress affects cardiovascular disease, it analyzes the potential of a number of therapeutic options that target these pathways. Understanding the complexity of the cellular redox system could lead to the development of better targeted interventions that facilitate patient recovery. Even as large-scale clinical trials of so-called 'simple' antioxidant approaches such as vitamins C and E s.