History taking and physical examination for the patient with liver disease -- Laboratory tests -- Liver biopsy and laparoscopy -- Imaging -- Interventional radiology procedures for diagnosis and treatment of hepatobiliary disease -- Endoscopic retrograde cholangiopancreatography -- Physioanatomic considerations -- Bilirubin metabolism and jaundice -- Hepatic histopathology -- Mehanisms of liver injury -- The liver in systemic disease -- Hematologic disorders and the liver -- Nutrition and the liver -- Hepatic fibrosis -- Portal hypertension and nonsurgical management -- Surgical management of portal hypertension -- Renal complications and hepatorenal syndrome -- Pulmonary manifestations of liver disease -- Ascites and spontaneous bacterial peritonitis -- Hepatic encephalopathy -- fulminant hepatic failure -- Gallstone disease: pathogenesis and treatment -- Primary sclerosing cholangitis -- Primary biliary cirrhosis -- Postoperative jaundice -- The hepatitis viruses -- Hepatitis A -- Hepatitis E -- Hepatitis B and D -- Hepatitis C -- Autoimmune hepatitis -- Alcoholic liver disease -- Drug-induced liver disease -- Mechanisms of drug-induced liver injury -- Wilson disease -- Hemochromatosis and iron storage disorders -- a₁-Antitrypsin deficiency -- Porphyrias -- Nonalcoholic fatty liver disease -- Vasucular diseases of the liver -- The liver in circulatory failure -- Benign solid tumors -- Nodular and cystic lesions -- Hepatocellular carcinoma -- Surgical options for the treatment of hepatocellular carcinoma -- Liver disease in infancy and childhood -- The liver in pregnancy -- Liver abscesses -- Parasitic diseases -- Bacterial and systemic infections -- Hepatobiliary manifestations of human immunodeficiency virus -- Granulomas of the liver -- Selection and timing of liver transplantation -- Immunosuppression: the global picture -- The first 6 months following liver transplantation -- The long-term care of transplanted patient -- The surgical options of liver transplantation -- Recurrent disease following liver transplantation -- The role of retransplantation -- Hepatobiliary complications of hematopoietic cell transplantation.