عنوان
پدید آورنده
موضوع
رده
کتابخانه
محل استقرار
LA2g62q2fq
انگلیسی
Primary cutaneous Epstein-Barr virus-positive diffuse large B-cell lymphoma (DLBCL) in a patient taking fingolimod
[Article]
Wills, Abby; Fan, Guang; Kim, Edward; Okada, Craig Y; White, Kevin P; Hopkins, R Samuel
A 55-year-old man with relapsing-remitting multiple sclerosis on fingolimod presented to the dermatology clinic with skin lesions on the left temple and cheek. Histopathology showed a diffuse infiltrate of enlarged, atypical lymphocytes throughout the dermis with an overlying grenz zone and a subpopulation of scattered smaller lymphocytes and plasma cells. Epstein-Barr virus-encoded RNA in situ hybridization stain was positive. Based on the morphologic and immunophenotypic findings, a diagnosis of EBV-positive diffuse large B-cell lymphoma was made. This case aims to raise awareness for the dermatologist that patients on fingolimod may be at increased risk of lymphoproliferative disorders.
2019
Dermatology Online Journal
25/9
Wills, Abby; Fan, Guang; Kim, Edward; Okada, Craig Y; White, Kevin P; Hopkins, R Samuel
مطالعه متن کتاب [Article]
275578
a
Y
