Deactivation of SARS-CoV-2 with pulsed-xenon ultraviolet light:
[Article]
Simmons, Sarah E; Carrion, Ricardo; Alfson, Kendra J; Staples, Hilary M; Jinadatha, Chetan; Jarvis, William R; Sampathkumar, Priya; Chemaly, Roy F; Khawaja, Fareed; Povroznik, Mark; Jackson, Stephanie; Kaye, Keith S; Rodriguez, Robert M; Stibich, Mark A
Implications for environmental COVID-19 control.
OBJECTIVES:Prolonged survival of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) on environmental surfaces and personal protective equipment may lead to these surfaces transmitting this pathogen to others. We sought to determine the effectiveness of a pulsed-xenon ultraviolet (PX-UV) disinfection system in reducing the load of SARS-CoV-2 on hard surfaces and N95 respirators. METHODS:Chamber slides and N95 respirator material were directly inoculated with SARS-CoV-2 and were exposed to different durations of PX-UV. RESULTS:For hard surfaces, disinfection for 1, 2, and 5 minutes resulted in 3.53 log10, >4.54 log10, and >4.12 log10 reductions in viral load, respectively. For N95 respirators, disinfection for 5 minutes resulted in >4.79 log10 reduction in viral load. PX-UV significantly reduced SARS-CoV-2 on hard surfaces and N95 respirators. CONCLUSION:With the potential to rapidly disinfectant environmental surfaces and N95 respirators, PX-UV devices are a promising technology to reduce environmental and personal protective equipment bioburden and to enhance both healthcare worker and patient safety by reducing the risk of exposure to SARS-CoV-2.