Introduction -- Scattering and particle interaction -- Space-time symmetries -- Internal symmetries -- Unitary groups and SU(3) -- SU(6) and quark model -- Color, gauge principle and quantum chromodynamics -- Heavy flavors -- Heavy quark effective theory -- Weak interaction -- Properties of weak Hadronic currents and Chiral symmetry -- Neutrino -- Electroweak unification -- Deep inelastic scattering -- Weak decays of heavy flavors -- Particle mixing and CP-violation -- Grand unification, supersymmetry and strings -- Cosmology and astroparticle physics -- Appendix A. Quantum field theory -- Appendix B. Renormalization group and running coupling constant.