عنوان

Glucose-sensing receptor in pancreatic beta-cells /

9789811300028

981130002X

9789811300011

9811300011

Glucose-sensing receptor in pancreatic beta-cells /

[Book]

edited by Itaru Kojima.

Singapore :

Springer,

[2018]

1 online resource (v, 71 pages) :

illustrations

Includes bibliographical references.

1 HISTORY OF THE RESEARCH ON THE GLUCOSE RECEPTOR -- 2 Cell-surface Glucoreceptor Recognizing Anomers of Glucose in Pancreatic b-cells -- 3 KATP CHANNEL-INDEPENDENT PATHWAY and THE GLUCORECEPTOR -- 4 Signaling System Activated by the Glucose-sensing Receptor -- 5 The Role of the Glucose-sensing Receptor in Glucose-induced Insulin Secretion in Pancreatic b-cells.

0

Since the 1970s, there has been much discussion about the "glucoreceptor" and "substrate site" and which of these two is the dominant theory, but new findings on the glucose-sensing receptor have now shed new light on the "glucoreceptor theory." This volume reviews recent advances concerning the glucose-sensing receptor in pancreatic beta-cells. The history of research into pancreatic beta-cells is long and complex; accordingly, the first chapters present the history of this field and explain the hypothesis of insulin secretion mechanisms: "glucoreceptor theory". Subsequent chapters examine the function and activity of the glucose-sensing receptor in pancreatic beta-cells, such as identification, channel pathway, receptor signal and physiological role. Readers will gain a thorough understanding of the glucose-sensing receptor and glucose metabolism in pancreatic beta-cells, new insights into the pathophysiology of diabetes, and learn about new targets for the treatment of diabetes.

Springer Nature

com.springer.onix.9789811300028

9789811300011

Glucose-- Receptors.

Pancreatic beta cells.

Pancreatic beta cells.

SCIENCE-- Life Sciences-- Biochemistry.

MED075000

MFG

Kojima, Itaru

20200823223313.0

pn

[Book]

Y