Intro; Preface; Acknowledgement; References; Table of contents; Chapter 1. Genetic diversity issues in animal populations in the genomic era; John A. Woolliams1* and J. Kor Oldenbroek2; Summary; 1.1 Introduction; 1.2 What is genetic diversity?; 1.3 Definitions of breeds; 1.4 State of genetic diversity; 1.5 Relevant developments in genomics for managing genetic diversity; 1.6 Application of genomics for breeding livestock and companion animals; 1.7 Opportunities to improve the management of genetic diversity; 1.8 The threats of genomics to the genetic diversity
1.9 Challenges for the management of genetic diversity with genomic toolsReferences; Chapter 2. Defining genetic diversity based on genomic tools; Jesús Fernández1* and Jörn Bennewitz2; Summary; 2.1 Introduction; 2.2 Measuring phenotypic diversity; 2.3 Use of pedigrees; 2.4 Molecular measures of diversity; 2.5 Advantages of genomic measures; 2.6 Relationship between molecular and pedigree measures; 2.7 Partition of diversity within and between breeds; 2.8 Using diversity measures for the prioritisation of breeds; 2.9 Towards accounting for adaptive diversity in conservation decisions
2.10 Cluster analysisReferences; Chapter 3. Genomic diversity in the domestication process; Miika Tapio1* and Saber Qanbari2; Summary; 3.1 Introduction; 3.2 What is domestication?; 3.3 Approaches to study the transition from wild to domesticated forms; 3.4 Domestication pathways and recruitment of wild diversity; 3.5 Domestic animals: main facts about the domestication of cattle, pigs, chicken, sheep, goat, horse and dog; 3.6 Intensifying management; 3.7 The future of domestication processes; 3.8 Conclusion; References; Chapter 4. Tracing domestication and selection in animal genomes
5.3 Genomic breeding strategies for maintaining diversity5.4 Management of merged populations with genomic tools; 5.5 Mating strategies for small populations; 5.6 Multiple breed genomic prediction; 5.7 Purging of deleterious mutations; 5.8 Marker-assisted introgression; 5.9 Genomic introgression; 5.10 Recovery from crossbreeding; References; Chapter 6. Management of cryo-collections with genomics tools; Peer Berg1* and Jack J. Windig2; Summary; 6.1 Introduction; 6.2 Role of cryo-conservation; 6.3 More efficient cryo-conservation with genomic tools
Saber Qanbari1* and Miika Tapio2Summary; 4.1 Introduction; 4.2 Human-mediated modifications to population demographic past; 4.3 Domestic animals are genetically diverse; 4.4 Domesticated traits: genes under the action of domestication; 4.5 Tests for selection in domesticated species; 4.6 Remaining challenge: to relate selective sweeps to functional traits; References; Chapter 5. Management of genetic diversity including genomic selection in small in vivo populations; Theo H.E. Meuwissen1* and J. Kor Oldenbroek2; Summary; 5.1 Introduction; 5.2 The goals of live conservation
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Recently developed genomic tools, like SNP-genotyping and whole genome sequencing, and their analysis, offer great opportunities for the conservation and utilisation of animal genetic diversity, both among and within breeds. These genomic tools can be used to detect potentially valuable rare alleles and haplotypes. They are important parts of the genetic diversity we need to conserve now for possible utilisation in the future. This book describes the use of genomic technology to define breeds and to assess important features in the history of breeds affecting the present genetic diversity. The management of genetic diversity with genomic tools is outlined both in vitro: gene banks, and in vivo: small populations of rare breeds or large populations with small effective population sizes. Special attention is given to the genomic management of populations of animals with high incidences of multiple genetic defects. This book is intended for MSc and PhD students as well as scientists working with small populations in animal breeding and in conservation programmes for rare breeds.