Anesthetic toxicity: an overview / Susan A. Rice, Kevin J. Fish -- Animal use in toxicity evaluation / Victor S. Lukas, Jr. -- Principles of epidemiology for evaluation of anesthetic toxicity / Kristie L. Ebi -- Metabolism of the volatile anesthetics / Lucy Waskell -- Hepatotoxicity of halogenated anesthetics / Max T. Baker, Russell A. Van Dyke -- Nephrotoxicity of volatile anesthetic agents / Kevin J. Fish -- Toxicity of local anesthetic agents / Hal S. Feldman -- Toxicity of nitrous oxide / Donald D. Koblin -- Reproductive and developmental toxicity of anesthetics in animals / Susan A. Rice -- Reproductive and developmental toxicity of anesthetics in humans / Kristie L. Ebi, Susan A. Rice -- Pharmacogenetics and anesthetic toxicity / Margaret Wood -- Malignant hyperthermia triggered by anesthetics / Marilyn Green Larach -- Immunosuppression in the postoperative period / Girish C. Moudgil -- Pulmonary effects of anesthesia / Brian P. Kavanagh, Ronald G. Pearl -- Biomarkers of anesthetic toxicity / C. Murray Ardies.