عنوان

Translational oral health research /

3319782053

9783319782058

3319782045

9783319782041

Translational oral health research /

[Book]

Jukka H. Meurman, editor.

Cham, Switzerland :

Springer,

[2018]

1 online resource (viii, 173 pages) :

illustrations

Includes bibliographical references and index.

Intro; Preface; Contents; 1: Translational Research in the Oral Health Sciences; 1.1 Definition of Translational Research in the Biomedical Sciences; 1.2 What Is Needed to Carry Out Biomedical Translational Research?; 1.2.1 Graduate Student Training; 1.2.2 Publication of Translational Team Science Research; 1.2.3 The Role of the Institution; References; 2: How Cross-Disciplinary Research Has Increased Our Understanding of Oral Mucosal Diseases; 2.1 Introduction; 2.2 What Is Research in Medical and Dental Schools?; 2.3 Multidisciplinary Clinics.

2.4 Assessment of Disease Severity and Treatment Responses in Oral Mucosal Disease2.5 Bullous Diseases; 2.6 Orofacial Granulomatosis; 2.7 Sjögren's Syndrome Clinic; 2.8 Clinical Oral Dryness Score (Fig. 2.7); References; 3: Epigenetics and Periodontitis: A Source of Connection to Systemic Diseases; 3.1 Introduction; 3.1.1 Molecular Regulation of the Immune Response; 3.1.2 Epigenetic Modifications of Gene Expression; 3.1.3 Immune Response in Periodontitis and Epigenetic Modifications; 3.1.4 DNA Methylation, Histone Modulation, and Other Gene Alterations; 3.2 Role of MicroRNAs.

3.3 Role of Long Noncoding RNAs3.4 Periodontitis, Epigenetic Alterations, and Systemic Diseases; 3.4.1 Obesity; 3.4.2 Cardiovascular Disease; 3.4.3 Rheumatoid Arthritis; 3.4.4 Cancer; 3.5 Concluding Remarks; References; 4: Topic: aMMP-8 Oral Fluid PoC Test; 4.1 Introduction; 4.2 Periodontal Health Versus Periodontal Inflammation and Clinical Measuring; 4.3 Validity, Sensitivity, and Specificity of Neutrophil Collagenase-2 (aMMP-8) System; 4.4 Justification for aMMP-8 Chairside Test in Reproductive Health Parameters.

4.5 Effect of Chronic Periodontitis on Erectile Dysfunction and Sperm Count4.6 Association Between Periodontitis and Conception; 4.7 Emerging Racial Differences on Chronic Periodontitis and Pregnancy Outcomes; 4.8 Role of aMMP-8 Chairside Test in Specific Periodontal Health Parameters; References; 5: Composite Biomaterials: From Lab to Clinics; 5.1 Introduction; 5.2 Dental Applications for FRC; 5.3 All Started from Removable Dentures; 5.4 Next Step: Fixed Dental Prostheses; 5.5 Into the Root Canal; 5.6 To Replace Amalgam; 5.7 Into Bone: Surgical Applications for FRC.

5.8 Role of Bioactive Glass5.9 The First Clinical Tests; 5.10 Future Aspects; References; 6: Translational Oral Health Research Implants and Bone Regeneration; 6.1 Introduction; 6.2 Surgical Placement Protocols; 6.3 Immediate Implants; 6.4 Early Implants; 6.5 Ridge Preservation; 6.6 Bone Regeneration of Residual Alveolar Ridges; 6.7 Future Technologies; References; 7: A Critical Reason for Conducting Clinical Trials Is that Results with Humans Are Not Necessarily Predictable from Preclinical Studies; 7.1 Introduction; 7.2 Cystic Fibrosis; 7.3 SCID X1.

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This book is the first to be devoted to translational research - which aims to expedite the transfer of knowledge gained in the lab to clinical practice - within the field of oral health. It is examined how basic sciences and basic research are providing new methods and materials that will enable clinicians to treat patients more effectively. Readers will gain a translational perspective on a variety of oral conditions and related systemic diseases. Individual chapters are devoted to such topics as dental biomaterials, implants, and tissue engineering. The importance of evidence-based research and the roles and comparative value of preclinical and clinical trials are also highlighted. Knowledge of translational and clinical research is essential in understanding how new inventions and developments are being accomplished, and what regulations and guidelines need to be taken into account when planning studies, and not forgetting the ethical aspects of any research. Translational Oral Health Research is the first book to be devoted entirely to the subject, and it will be of interest to both researchers and practitioners.

Springer Nature

com.springer.onix.9783319782058

Translational oral health research.

9783319782041

Dentistry-- Research.

Oral medicine-- Research.

Dentistry-- Research.

Dentistry.

MEDICAL-- Surgery-- General.

Oral & maxillofacial surgery.

MED-- 085000

MMD

Meurman, Jukka H.

20200823113053.0

pn

[Book]

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