عنوان

Label-free biosensing :

3319752200

9783319752204

3319752197

9783319752198

Label-free biosensing :

[Book]

advanced materials, devices and applications /

volume editors, Michael J. Schöning, Arshak Poghossian ; with contributions by N. Abramova [and others].

Cham, Switzerland :

Springer,

[2018]

©2018

1 online resource

Springer series on chemical sensors and biosensors : methods and applications ;

16

Includes bibliographical references and index.

Intro; Series Editor; Aims and Scope; Preface; Contents; Nanomaterial-Modified Capacitive Field-Effect Biosensors; 1 Introduction; 2 Capacitive EIS Sensors Modified with AuNP/Molecule Hybrids; 2.1 Preparation of AuNP-Modified EIS Sensors and Measurement Setup; 2.2 Functioning of EIS Sensors Modified with AuNP/Molecule Hybrids; 2.3 Detection of Cytochrome c; 2.4 Detection of Poly-d-lysine; 2.5 Detection of LbL Adsorption of Oppositely Charged PE Macromolecules and Multilayer Formation; 2.6 Enzyme Logic Gates Based on an AuNP-Modified EIS Sensor; 3 Polyelectrolyte-Modified EIS Sensors

3.1 Label-Free Detection of DNA with PAH-Modified EIS Sensor3.2 Biosensors Based on an EIS Sensor Modified with a PAH/Enzyme Multilayer; 4 Summary and Outlook; References; Silicon Nanowire Field-Effect Biosensors; 1 Introduction: Ion-Sensitive Field-Effect Transistors; 2 Sensor Operation and Readout Strategies; 2.1 Surface-Charge Sensing; 2.2 Beyond Surface-Charge Sensing; 3 Silicon Nanowire Ion-Sensitive Field-Effect Transistors; 3.1 Fabrication of SiNW ISFETs; 3.2 Limitations of SiNW-based ISFETs; 3.2.1 Downscaling of ISFETs; 3.2.2 Surface Functionalization

3.2.3 Gate Oxide and Sensor Configuration3.2.4 Sensing in Physiological Solutions; 4 Competing Platforms and New Concepts; 4.1 New Materials and Nanowire Hybrids; 4.2 Microfluidic Integration; 5 Conclusions; References; Label-Free Biosensors Based on III-Nitride Semiconductors; 1 Introduction; 2 Group III-Nitrides; 2.1 Basic Properties; 2.2 Polarization in Group III-Nitrides; 2.3 Indium Nitride; 2.4 Summary of Features Relevant for Biosensors; 2.5 Overview on Nitride-Based Biosensors; 3 High-Electron-Mobility Transistor Sensors; 3.1 Sensor Structure and Technology; 3.2 pH Sensors

3.3 Monitoring Biochemical Reactions4 Surface Treatment and Stability; 4.1 Oxidation; 4.2 Stability in Water; 4.3 Cleaning of GaN Surfaces; 4.4 Wetting Behavior; 4.5 Impact of Device Processing; 5 Biofunctionalization of the Surfaces; 6 BioFETs (Detection of Biomarkers); 6.1 Enzyme-Modified Sensor: EnFET; 6.2 Immunologically Based Sensor: ImmunoFET; 6.3 DNA-Modified Sensor: DNA-FET; 6.4 Advanced Measurement Schemes; 6.4.1 Subthreshold Operation; 6.4.2 Impedance Spectroscopy; 6.4.3 Dynamic Measurements; 7 Cell Proliferation; 8 Cell-FETs (Monitoring Living Cells); 9 Further Biosensors

9.1 Electrical Biosensors: Nanowires9.2 Mechanical Biosensors: Electroacoustic Resonators; 9.3 Optical Biosensors; 10 Multiparameter Systems; 11 Conclusions; References; (Bio- )chemical Sensing and Imaging by LAPS and SPIM; 1 Introduction; 2 Principles of LAPS and SPIM; 2.1 Measurement Set-Up; 2.2 Generation of Photocurrent Dependent on Analyte Concentration; 2.3 Photocurrent-Voltage and Phase-Voltage Characteristics; 2.4 Equivalent Circuit of the LAPS; 2.5 Operation Modes; 2.5.1 Constant-Bias Mode; 2.5.2 Constant-Current Mode; 2.5.3 Potential-Tracking Mode; 2.5.4 Phase Mode; 2.5.5 SPIM Mode

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"This volume summarizes the state-of-the-art technologies, key advances and future trends in the field of label-free biosensing. It provides detailed insights into the different types of solid-state, label-free biosensors, their underlying transducer principles, advanced materials utilized, device-fabrication techniques and various applications. The book offers graduate students, academic researchers, and industry professionals a comprehensive source of information on all facets of label-free biosensing and the future trends in this flourishing field. Highlights of the subjects covered include label-free biosensing with:· semiconductor field-effect devices such as nanomaterial-modified capacitive electrolyte-insulator-semiconductor structures, silicon nanowire transistors, III-nitride semiconductor devices and light-addressable potentiometric sensors· impedimetric biosensors using planar and 3D electrodes· nanocavity and solid-state nanopore devices · carbon nanotube and graphene/graphene oxide biosensors· electrochemical biosensors using molecularly imprinted polymers· biomimetic sensors based on acoustic signal transduction· enzyme logic systems and digital biosensors based on the biocomputing concept· heat-transfer as a novel transducer principle· ultrasensitive surface plasmon resonance biosensors · magnetic biosensors and magnetic imaging devices"--

Springer Nature

com.springer.onix.9783319752204

Label-free biosensing.

9783319752198

Biosensors.

Biosensing Techniques.

Biology, life sciences.

Biomedical engineering.

Biophysics.

Biosensors.

HEALTH & FITNESS-- Holism.

HEALTH & FITNESS-- Reference.

MEDICAL-- Alternative Medicine.

MEDICAL-- Atlases.

MEDICAL-- Essays.

MEDICAL-- Family & General Practice.

MEDICAL-- Holistic Medicine.

MEDICAL-- Osteopathy.

Nanotechnology.

Precision instruments manufacture.

HEA-- 012000

HEA-- 020000

MED-- 004000

MED-- 029000

MED-- 040000

MED-- 092000

MED-- 101000

MED-- 109000

TBN

TBN

Poghossian, Arshak

Schöning, Michael J.

20200823105655.0

pn

[Book]

Y