عنوان

Hybrid systems biology :

3030280411

303028042X

3030280438

9783030280413

9783030280420

9783030280437

9783030280413

Hybrid systems biology :

[Book]

6th International Workshop, HSB 2019, Prague, Czech Republic, April 6-7, 2019 : revised selected papers /

Milan Češka, Nicola Paoletti (eds.).

Cham, Switzerland :

Springer,

[2019]

1 online resource (xvi, 181 pages) :

illustrations (some color)

Lecture notes in bioinformatics,

LNCS sublibrary: SL 8 -- Bioinformatics

11705

1611-3349 ;

Includes bibliographical references and index.

A multimodular system to study the impact of a focal lesion in neuronal cell cultures -- Reachability analysis and hybrid systems biology -- In Memoriam Oded Maler -- Reaction networks, oscillatory motifs and parameter estimation in biochemical systems -- Fixed-point computation of equilibria in biochemical regulatory networks -- Rejection-based simulation of stochastic spreading processes on complex networks -- Controlling noisy expression through auto regulation of burst frequency and protein stability -- Extracting landscape features from single particle trajectories -- A hybrid HMM approach for the dynamics of DNA methylation -- Using a hybrid approach to model central carbon metabolism across the cell cycle -- Data-informed parameter synthesis for population Markov chains-. rPrism -- A software for reactive weighted state transition models -- Hybrid modeling of metabolic-regulatory networks.

0

This book constitutes the thoroughly refereed proceedings of the 6th International Workshop on Hybrid Systems Biology, HSB 2019, held in Prague, Czech Republic, in April 2019. The 8 full papers presented in this book together with 1 short paper and 3 invited papers were carefully reviewed and selected from 13 submissions. They cover topics such as: modeling and analysis of metabolic, signaling, and genetic regulatory networks in living cells; models of tissues, organs, physiological models; models and methods coping with incomplete, uncertain and heterogeneous information including learning for biological systems, parametric synthesis and inference; stochastic and hybrid models in biology; hierarchical systems for multi-scale, multi-domain analysis; abstraction, approximation, discretization, and model reduction techniques; modeling, analysis and design for synthetic biology, cyber-biological systems and biomedical studies (e.g. therapies, teleoperation); game-theoretical frameworks and population models in biology (e.g. mixed-effects and Bayesian modeling); biological applications of quantitative and formal analysis techniques (e.g. reachability computation, model checking, abstract interpretation, bifurcation theory, stability and sensitivity analysis); efficient techniques for combined and heterogeneous (stochastic/deterministic, spatial/non-spatial) simulations for biological models; modeling languages and logics for biological systems with related analysis and simulation tools; and control architectures of biological systems including biology-in-the-loop systems and bio-robotics.

Springer Nature

com.springer.onix.9783030280420

9783030280413

9783030280437

Hybrid systems, Congresses.

Systems biology, Congresses.

Hybrid systems.

Systems biology.

COM014000

PSA

PSA

UB

Češka, M., (Milan)

Paoletti, Nicola

HSB (Workshop)(6th :2019 :, Prague, Czech Republic)

20200823093836.0

pn

[Book]

Y