عنوان
پدید آورنده
موضوع
رده
RS160 .N38 2018
RS160
.
N38
2018
کتابخانه
محل استقرار
3030005453
9783030005450
3030005445
9783030005443
Natural products as source of molecules with therapeutic potential :
[Book]
research & development, challenges and perspectives /
editor, Valdir Cechinel Filho.
Cham, Switzerland :
Springer,
[2018]
1 online resource
Includes index.
Intro; Dedication; Acknowledgments; Contents; About the Editor; Medicinal Plants and Phytomedicines; 1 Introduction; 2 Quality Control of Phytomedicines; 2.1 Quality and Efficacy of Plant Material; 2.2 Production Methods; 3 Medicinal Teas Today; 4 Modern Phytotherapy; 4.1 New Scientific Screening; 4.2 Mechanism of Action; 4.3 Synergy; 5 Some Selected Phytomedicines; 5.1 Ginkgo biloba (Ginkgo); 5.2 Serenoa repens (Saw Palmetto); 5.3 Valeriana officinalis (Valerian); 5.4 Hypericum perforatum (St. John's Wort); 5.5 Allium sativum (Garlic); 5.6 Piper methysticum; 5.7 Glycine max (Soy)
3.2 Kefir3.3 Kombucha; 4 Prebiotics; 5 Synbiotics; 6 Conclusions; References; The Role of Flavonoids as Modulators of Inflammation and on Cell Signaling Pathways; 1 Introduction; 2 Absorption and Metabolism of Flavonoids; 3 Inflammation; 3.1 Inflammatory Mediators; 3.1.1 Nitric Oxide; 3.1.2 Arachidonic Acid Metabolites; 3.1.3 Cytokines; 3.1.4 Chemokines; 3.1.5 Cell Adhesion Molecules; 3.2 Inflammation-Associated Intracellular Signaling Pathways; 3.2.1 Nuclear Transcription Factor Kappa-B (NF-kB) Pathway; 3.2.2 Signal Transducer and Activator of Transcription (STAT) Protein Family
4 Production of Antimicrobials Through Plant Tissue Cultures4.1 Production of Antimicrobials Through Plant Cell Cultures; 4.2 Production of Antimicrobials Through Plant Organ Cultures; 4.3 Production of Antimicrobials Through Plantlets Propagated In Vitro; 5 Conclusions; References; Liquid Chromatography for Plant Metabolite Profiling in the Field of Drug Discovery; 1 Introduction; 2 Sample Preparation; 3 Development of the Metabolite Profile; 3.1 Thin-Layer Chromatography; 3.2 Column Chromatography; 3.3 Detectors; 3.3.1 Spectroscopic Detection; 3.3.2 Mass Spectrometric Detection; Ionization
5.8 Matricaria chamomilla5.9 Maytenus ilicifolia; 5.10 Ilex paraguariensis; 5.11 Cynara scolymus L.; 5.12 Phyllanthus niruri; 6 Case Study: Development of the Phytomedicine from Biodiversity; 7 Conclusions; References; Plant Products with Antifungal Activity: From Field to Biotechnology Strategies; 1 Introduction; 2 Human Fungal Diseases; 3 Antifungal Susceptibility Methods; 3.1 Anti-Candida Plant Products; 3.2 Anti-dermatophytes Plant Products; 3.3 Anti-Malassezia Plant Products; 3.4 Anti-Aspergillus Plant Products; 3.5 Anti-Cryptococcus Plant Products
Mass AnalysisFragmentation; From MS Spectra to Compound Identification; 4 Pharmacological Evaluation; 5 Multivariate Data Handling of Chromatographic Fingerprints; 6 Applications of Metabolite Profile; 6.1 Linked to In Vitro Reaction Assays; 6.2 Linked to In Vitro Enzymatic Assays; 6.3 Linked to In Vivo Assays; 7 Conclusions; References; Functional Foods as Source of Bioactive Principles: Some Marked Examples; 1 Introduction; 2 Functional Foods; 2.1 Curcuma; 2.2 Garlic; 2.3 Omega-3; 2.4 Olive Oil; 2.5 Tea; 2.6 Ginger; 2.7 Broccoli; 2.8 Grape; 2.9 Black Pepper; 3 Probiotics; 3.1 Yogurt
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This book addresses the highly relevant and complex subject of research on drugs from natural products, discussing the current hot topics in the field. It also provides a detailed overview of the strategies used to research and develop these drugs. Respected experts explore issues involved in the production chain and when looking for new medicinal agents, including aspects such as therapeutic potential, functional foods, ethnopharmacology, metabolomics, virtual screening and regulatory scenarios. Further, the book describes strategic methods of isolation and characterization of active principles, biological assays, biotechnology of plants, synthesis, clinical trials and the use of tools to identity active principles.
Springer Nature
com.springer.onix.9783030005450
9783030005443
9783030005467
Biological products.
Drug development.
Natural products.
Biological Products-- therapeutic use.
Biological products.
Drug development.
MEDICAL-- Pharmacology.
Natural products.
MED-- 071000
PSB
PSB
615
.
1/9
23
RS160
.
N38
2018
Cechinel-Filho, Valdir
20200823071923.0
pn
مطالعه متن کتاب [Book]
Y
