عنوان
پدید آورنده
موضوع
رده
R853.C55 C53 2012eb
R853
.
C55
C53
2012eb
کتابخانه
محل استقرار
1439839883
9781439839881
1439839875
9781439839874
Adaptive design methods in clinical trials /
[Book]
Shein-Chung Chow, Mark Chang.
2nd ed.
Boca Raton, FL :
CRC Press,
©2012.
1 online resource (xvi, 358 pages) :
illustrations
Chapman & Hall/CRC biostatistics series
"A Chapman & Hall book."
Includes bibliographical references and index.
Protocol amendment -- Adaptive randomization -- Adaptive hypotheses -- Adaptive dose-escalation trials -- Adaptive group sequential design -- Statistical tests for adaptive seamless designs -- Adaptive sample size adjustment -- Two-stage adaptive design -- Adaptive treatment switching -- Bayesian approach -- Biomarker adaptive trials -- Target clinical trials -- Sample size and power estimation -- Clinical trial simulation -- Regulatory perspectives : a review of FDA draft guidance.
0
With new statistical and scientific issues arising in adaptive clinical trial design, including the U.S. FDA's recent draft guidance, a new edition of one of the first books on the topic is needed. Adaptive Design Methods in Clinical Trials, Second Edition reflects recent developments and regulatory positions on the use of adaptive designs in clinical trials. It unifies the vast and continuously growing literature and research activities on regulatory requirements, scientific and practical issues, and statistical methodology. New to the Second Edition Along with revisions throughout the text.
Ingram Content Group
TANDF_219687
Adaptive design methods in clinical trials.
9781439839874
Adaptive sampling (Statistics)
Clinical trials-- Statistical methods.
Clinical trials.
Experimental design.
Biometry-- methods.
Clinical Trials as Topic-- methods.
Models, Statistical.
Research Design.
Adaptive sampling (Statistics)
Clinical trials-- Statistical methods.
Clinical trials.
Experimental design.
MEDICAL-- Laboratory Medicine.
MED-- 047000
610
.
72/4
23
R853
.
C55
C53
2012eb
2012
A-720
QV
20
.
5
Chow, Shein-Chung,1955-
Chang, Mark.
20200822183154.0
pn
مطالعه متن کتاب [Book]
Y
