The role of lysophosphatidylcholine acyltransferase-2 (LPCAT-2) in inflammatory responses
[Thesis]
Alrammah, Hanaa
University of Plymouth
2018
Thesis (Ph.D.)
2018
Sepsis is the overwhelming inflammatory response to infection, especially bacterial infection and associated bacterial products. It has major healthcare impacts, affecting an estimated 19-30 million persons/year worldwide with a mortality of 30-70%. Despite intense research, no specific therapy has been established for sepsis and in addition to the high mortality, the associated economic costs are very high. For example, recent data shows that the annual cost of patients with sepsis is more than