عنوان
پدید آورنده
موضوع
رده
کتابخانه
محل استقرار
TL48619
انگلیسی
Surface engineered biosensors for the early detection of cancer
[Thesis]
Muhymin Islam
Iqbal, Samir
The University of Texas at Arlington
2015
187
Committee members: Butler, Donald; Ghosh, Santaneel; Kim, Young-Tae; Magnusson, Robert
Place of publication: United States, Ann Arbor; ISBN=978-1-339-42914-4
Ph.D.
Electrical Engineering
The University of Texas at Arlington
2015
Cancer commences in the building block of human body which is cells and in most of the cases remains silent at early stage. Diseases are only expressed at molecular and cellular level at primary stages. Recognition of diseases at this micro and nano level might reduce the mortality rate of cancer significantly. This research work aimed to introduce novel electronic biosensors for for identification of cancer at cellular level. The dissertation study focuses on 1) Label-Free Isolation of Metastatic Tumor Cells Using Filter Based Microfluidic device; 2) Nanotextured Polymer Substrates for Enhanced Cancer Cell Isolation and Cell Growth; 3) Nanotextured Microfluidic Channel for Electrical Profiling and Detection of Tumor Cells from Blood; and 4) Single Biochip for the Detection of Tumor Cells by Electrical Profile and Surface Immobilized Aptamer. Standard silicon processing techniques were followed to fabricate all of the biosensors. Nantoextruing and surface functionalizon were also incorporated to elevate the efficiency of the devices.
Biomedical engineering; Electrical engineering; Nanotechnology
Applied sciences;Aptamer;Biosensors;Cancer;Microfluidics;Nanotexture;Translocation profile
Sadegh-Vaziri, Persheng
Iqbal, Samir
Electrical Engineering
The University of Texas at Arlington
1761573953; 10003854
مطالعه متن کتاب p
[Thesis]
276903
a
Y
