edited by Luigi Minetti, Giuseppe D'Amico, Claudio Ponticelli.
Dordrecht
Springer Netherlands
1988
(320 pages)
Developments in nephrology, 22.
I. The Plasma Cell Dyscrasias --; 1. A perspective of plasma cell dyscrasias: clinical implications of monoclonal light chains in renal disease --; 2. Genotypic and phenotypic diversity of plasma cell myeloma --; 3. Immunoglobulin synthesis in plasma cell dyscrasias with renal lesions --; 4. Renal amyloidosis: new perspectives --; 5. Amyloidogenesis and light chains --; 6. Physiopathological aspects of plasma cell dyscrasias --; II. Light Chain Nephrotoxicity --; 1. Glomerular and associated tubular injury by light chains. The spectrum of damage and effect of treatment --; 2. Effect of light chains on proximal tubule function --; 3. Pathophysiological aspects of myeloma cast nephropathy --; 4. Light chain nephrotoxicity: insights from a rat model of myeloma --; 5. Light chain-related tubulointerstitial nephropathy --; 6. The pathogenesis of cast nephropathy --; 7. Light chain nephrotoxicity --; III. The Kidney Involvement in Plasma Cell Dyscrasias --; 1. Kidney in multiple myeloma and related disorders --; 2. Histological, histochemical and ultrastructural features of myeloma kidney --; 3. Monoclonal immunoglobulin deposition disease: immunopathologic aspects of renal involvement --; 4. The glomerulonephritis of essential mixed cryoglobulinemia --; 5. Clinical spectrum of tubular disorders from light chains --; 6. Renal amyloidosis --; Retrospective collaborative study --; 7. Kidney involvement in light chain deposition disease --; 8. Some aspects of kidney involvement in plasma cell dyscrasias --; IV. The Therapeutic Approach --; 1. Controlled trial of plasma exchange in rapidly progressive renal failure --; 2. Prevention and treatment of hyperviscosity syndrome --; 3. Implications of renal failure in mUltiple myeloma --; 4. Uraemia in myeloma: management and prognosis --; 5. Therapeutic prospects in amyloidosis --; 6. Sundries on therapy of multiple myeloma and amyloidosis and their renal consequences --; V. --; Conclusions --; Index of subjects.
Medicine.
Nephrology.
edited by Luigi Minetti, Giuseppe D'Amico, Claudio Ponticelli.