1 Basic methodology in the molecular characterization of genes --; 2 Genetic linkage analysis in hypertension: principles and practice --; 3 Molecular biology of renin --; 4 Discovery of genes for essential hypertension --; 5 Molecular regulation of smooth muscle contraction --; 6 Molecular biology of adrenergic receptors --; 7 Transgenic rats in hypertension research --; 8 Cloning, expression and regulation of angiotensin II receptors --; 9 Molecular biology and biochemistry of the natriuretic peptide system --; 10 Molecular regulation of plasma and tissue angiotensinogen --; 11 Molecular biology of oncogenes and cardiovascular hypertrophy --; 12 Molecular and cellular biology of endothelin and its receptors --; 13 Finding genes that cause human hypertension --; 14 Methods for the reduction or ablation of gene function --; 15 Molecular biology of the angiotensin I converting enzyme --; 16 The molecular biology of the kallikrein-kinin system --; 17 Prostaglandins and their receptors --; 18 The role of apolipoproteins in lipid metabolism and atherogenesis: aspects in man and mice --; 19 Vasopressin in the regulation of body functions --; 20 Beyond genetic markers: hypertension genes --; 21 Molecular aspects of signal transduction of shear stress in the endothelial cell.
This book represents a cross-sectional account of the advances that the ability to probe the very roots of biological function have produced in the field of cardiovascular medicine. It arose from a series of articles published over the last few years in the Journal of Hypertension, bringing together an illustrous panel of experts from a broad spectrum of theoretical and applied areas of science.