عنوان

Animal Models - Disorders of Eating Behaviour and Body Composition

940159662X

9789401596626

b592006

Animal Models - Disorders of Eating Behaviour and Body Composition

[Book]

edited by John B. Owen, Janet L. Treasure, David A. Collier.

Dordrecht

Springer Netherlands

2001

(xi, 251 pages)

1 Human disorders of eating behaviour and body composition --; 1 Obesity syndromes --; 2 The spectrum of eating disorders in humans --; 3 Free-choice diet selection --; the economics of eating --; 2 Diet selection and aberrations of body composition --; 4 Diet selection in wild animals --; 5 The animal within: lessons from the feeding behaviour of farm animals --; 6 Exercise and diet-induced obesity in mice --; 3 Genetic models of animal obesity --; 7 The obesity (ob) gene and leptin in animal models of obesity --; 8 Genetic susceptibility of rodents to diet-induced obesity --; 4 Genetic susceptibility to leanness in animals --; 9 Muscle enhanced traits in cattle and sheep --; 10 The halothane gene and leanness and stress susceptibility in pigs --; 5 Anorexia models --; 11 The Anorexia Mouse --; 12 Anorexia-like wasting syndromes in pigs --; 13 Laboratory animal models for investigating the mechanisms and function of parasite-induced anorexia --; Conclusion Implications for understanding and treating human eating disorders.

This book deals with a novel aspect of a topical problem that is of widespread concern. Obesity and other eating disorders are significant human health problems that are proving highly resistant to prevention and cure. The recognition of important genotype/environment interaction in the causation of these problems and of the extensive genetic homology of higher animals justifies the importance of cross-species comparisons. The book covers observations made on animals in the wild as well as experimental data on laboratory animals and farm animals in order to lay out the basic genetic and environmental factors underlying the control of appetite (including diet selection) and body weight. Breakdown in these intricate mechanisms are then compared to examine the possible common candidate genes and their interaction with non-genetic factors, particularly the availability of diet choice and of levels of body activity. Animals have much to tell us about these mysteries and may significantly aid progress in dealing with what are still highly intractable and serious diseases of the modern world.

Human genetics.

Medicine.

Neurosciences.

edited by John B. Owen, Janet L. Treasure, David A. Collier.

David A Collier

Janet L Treasure

John B Owen

[Book]

Y