Front Matter; TLRs as bacterial sensors; Toll-like receptors and rheumatoid arthritis: is there a connection?; Toll-like receptor 9 and systemic autoimmune diseases; Toll-like receptors and airway disease; Toll-like receptors and vascular disease; Toll-like receptors and inflammatory bowel disease; Toll-like receptor signaling in the liver; Toll-like receptors as key sensors of viral infection; IRAK-4: A key kinase involved in toll-like receptor signaling and resistance to bacterial infection; Endogenous regulation of toll-like receptor signalling.
A repertoire of ten TLRs mediate the response to microbes that infect mammals. This volume covers the understanding of TLRs, and their role in inflammation. Given the primacy of TLRs in the inflammatory process and their role in inflammatory diseases, this book is of interest to researchers working in inflammation and immunology.