عنوان

Experimental and Clinical Effects of L-Asparaginase

3642999840

3642999867

9783642999840

9783642999864

b577272

Experimental and Clinical Effects of L-Asparaginase

[Book]

edited by E. Grundmann, H.F. Oettgen.

Berlin, Heidelberg

Springer Berlin Heidelberg

1970

Recent Results in Cancer Research, Fortschritte der Krebsforschung / Progrès dans les recherches sur le cancer, 33.

Opening Remarks --; I. L-Asparaginase and the Asparagine Metabolism --; Asparaginase and Cancer --; Yesterday and Today --; L-Asparaginase: Early Findings and Current Studies on the Metabolism of L-Asparagine in Lymphoma Cells --; Studies on the Control of Asparagine Biosynthesis in Mamalian Tissues --; II. Preparative Aspects --; Isolation and Crystallisation of L-Asparaginase from E. coli --; Biochemical Characterization of L-Asparaginases from E. coli --; Some Physicochemical Aspects of L-Asparaginase Therapy --; III. Pharmacokinetics --; The Distribution and Clearance of L-Asparaginase --; Pharmacokinetic Behavior of L-Asparaginase in Men and in Animals --; The Partitioning of L-Asparaginase between Blood and Lymph --; Critical Influence of an Enzyme-Elevating Virus upon Long-Term Remissions of Mouse Leukemia Following Asparaginase Therapy --; IV. Experimental Effects --; Experimental Studies with L-Asparaginase in Mouse Leukemias --; Experimental Investigations on Problems of the Clinical Use of L-Asparaginase --; Studies on the Glutaminase Activity of E. coli Asparaginase in Tissue Culture --; L-Asparaginase in the Treatment of Neoplastic Diseases of the Dog, Cat and Cow --; The Cytomorphological Effects of L-Asparaginase in Sensitive Cells --; Inhibitation by L-Asparaginase from E. coli of Human Malignant Melanoma Cells Growing in vitro --; Influence of L-Asparaginase Preparations of E. coli and Agouti Serum on the Homograft Reactivity in the Mouse --; Studies on the Immunosuppressive Activity of L-Asparaginase --; Experimental Immunosuppression with L-Asparaginase --; V. Animal Toxicity --; Experimental Studies on the Toxicity of Crasnitin in Animals --; VI. Resistance Problems --; The Effect of Asparaginase on Some Animal-Tumors --; Studies of Resistance to L-Asparaginase in Human Leukemia --; The Antigenicity of E. coli-Asparaginase --; Studies on Antibody Formation in Patients Treated with L-Asparaginase --; VII. Clinical Effects and Side Effects --; Treatment of Acute Leukemia with L-Asparaginase --; Clinical Experience with L-Asparaginase --; Clinical Experience with L-Asparaginase --; Results of a Cooperative Study with L-Asparaginase in Human Leukemias. Report of the Section 'Oncology' of the Paul-Ehrlich-Society for Chemotherapy --; Clinical Experience with L-Asparaginase --; Treatment of Acute Leukemia with L-Asparaginase --; Preliminary Results on 84 Cases --; The Place of the L-Asparaginase in the Treatment of Acute Leukemias --; With Reference to Blastogenesis Inhibition by L-Asparaginase --; Some Clinical Observations on the Treatment with L-Asparaginase of the Acute Leukemias --; Clinical Trials of Asparaginase in Chemotherapy-Resistant Acute Leukemias --; Use of Asparaginase in Conjunction with Cytosine Arabinoside in Acute Leukemia in Children --; Clinical Studies with L-Asparaginase in Dermatomyositis --; Blood Coagulation Changes under L-Asparaginase Therapy --; The Hemostatic Defect Induced by Treatment with Asparaginase in Leukemia --; Dysmetabolic and Neurological Complications in Leukemic Patients Treated with L-Asparaginase --; A Summary of the Clinical Status of Asparaginase.

Medicine.

edited by E. Grundmann, H.F. Oettgen.

E Grundmann

H F Oettgen

[Book]

Y