(360 pages 325 illustrations, 109 illustrations in color.)
I. The structure of the immune system and the relationship between its components.- II. Immunology of the gastrointestinal tract.- III. Immunology of the liver.- IV. Polyclonal gammopathies.- V. Monoclonal gammopathies.- VI. The oligoclonal gammopathies.- VII. The heavy chain disease.- VIII. Forms and differentiations of the plasma cell tumors.- IX. Prognosis and epidemiology of plasmocytomas.- X. Forms and causes of coagulation disturbances in monoclonal gammopathies.- XI. Organ destructive effect of the light chain. Myeloma kidney.- XII. Amyloidosis.- XIII. Neurologic symptoms and complications of monoclonal gammopathies.- XIV. Chromosome studies in monoclonal gammopathies.- XV. Therapy of the plasma cell tumors.- XVI. The possibilities and limits of the plasma exchange in the treatment of monoclonal gammopathies.
Although plasma cell tumors are still an enigma, the author provides an excellent overview of all aspects of examination and treatment of gammopathies, based on 30 years of experience examining more than 1500 patients. Several new modes of treatment which have improved patient quality of life have been developed over the past decades, including bone marrow transplantation. All of these have been dealt with in this publication.