I. The development of ideas on the synapse --; II. Structural features of chemically transmitting synapses --; III. Physiological properties of chemically transmitting synapses in the resting state --; IV. Excitatory postsynaptic responses to presynaptic impulses --; V. Excitatory transmitter substances --; VI. The release of transmitter by presynaptic impulses --; VII. The generation of impulses by the excitatory postsynaptic potential and the endplate potential --; VIII. The presynaptic terminals of chemically transmitting synapses --; IX. Excitatory synapses operating by electrical transmission --; X. The postsynaptic electrical events produced by chemically transmitting inhibitory synapses --; XI. The ionic mechanism generating the inhibitory postsynaptic potential --; XII. Inhibitory transmitter substances --; XIII. Pathways responsible for postsynaptic inhibitory action --; XIV. Inhibitory synapses operating by electrical transmission --; XV. Presynaptic inhibition --; XVI. The trophic and plastic properties of synapses --; Epilogue --; References.
I must thank my friend, Professor HANS WEBER, for being, as it were, the prime mover in causing this book to be written. He persuaded me in 1960 to contribute a review to the Ergebnisse der Physiologie. As originally planned, it was to be relatively short. However, the interest and scope of the whole subject of synapses stimulated me to write a much more comprehensive and extensive account. I was not even then satisfied, particularly as so many new and attractive investigations and ideas were being evolved during and after the writing of this review; and during the writing of this book most in.