I. Basic Anatomy and Physiology --;1. Historical Introduction to Gonadal Regulation of the Uterus and the Menses --;2. The Neuroendocrine System --;3. Placental Endocrinology --;II. Hormonal Physiology --;4. Hormonal Physiology of the Ovary and Adrenal Cortex --;5. Physiology of Relaxin --;6. Normal Growth and Development of the Female --;7. Thyroid Function and Disease in the Female --;III. Diagnostic Procedures --;8. Hormone Assays in Endocrine Systems --;9. Hormonal Cytopathology of the Vagina --;10. Cervical Mucus --;11. Endometrium --;12. Diagnostic Imaging --;13. Endoscopic Procedures --;IV. Endocrine Disorders in the Female --;14. Ovarian Dysgenesis and Related Genetic Disorders --;15. Female Pseudohermaphroditism in 21-Hydroxylase Deficiency --;16. Hypothalamic-Pituitary Disease --;17. Secondary Amenorrhea and the Menopause --;18. Endometriosis --;19. Dysmenorrhea and Prostaglandins --;20. Fertility following Steroidal Oral Contraception and Diethylstilbestrol Exposure --;21. Anorexia Nervosa and Other Weight-Loss-Associated Amenorrheas --;22. Premenstrual Tension and Idiopathic Edema --;23. Hirsutism and Virilism in Women --;24. Lactation and Galactorrhea --;25. Hormone-Producing Tumors of the Ovary and Placenta --;26. Steroid Receptors in Breast, Uterine, and Ovarian Malignancy: Diagnostic and Therapeutic Applications --;27. Understanding and Managing of Pregnancy in Women with Diabetes Mellitus --;V. Infertility and its Future --;28. Investigation of the Infertile Couple --;29. Male Infertility --;30. Surgical Treatment of Infertility --;31. Medical Treatment of Infertility --;32. In Vitro Fertilization --;VI. New Frontiers in Gynecologic Endrocrinology --;33. Endocrine Control of the Secretory Immune System in the Reproductive Tract of the Female: Response of IgA, IgG, and Secretory Component in the Uterus to Sex Hormones --;34. Epidermal Growth Factor and Its Receptor and Their Possible Relationships to Gynecologic Endocrinology --;Glossary of Abbreviations.
It has been exactly five years since I was privileged to write the foreword for the previous edition of this distinguished book on gynecologic endocrinology. Reproductive endocrinology has been established as a separate respected area in the general field of endocrinology, as well as in obstetrics and gynecology. Years ago the reproductive endocrinologist took long periods of time to answer questions, since most of the studies done then used bioassay methods. These studies were hastened by the work of Berson and Yalow with their development of the radioimmunoassay. They were later awarded the Nobel Prize for this work, since it unlocked many avenues of investigation in the field of endocrinology. It is now possible to measure small quantities of hormones in various biological tissues. Since that time high-pressure liquid chro matography and mass spectrometry have unlocked further secrets in this field with their capability of measuring ever smaller quantities of substances as well as their metabolites. Giant strides have been made in other diagnostic methods that interface with gynecologic endocrinology, notably in the field of radiology in the arena of tomography and CAT scans, and now nuclear magnetic resonance. Progress will be pushed still further, and this fourth edition again identifies the leading edge of knowledge. Such new areas embrace the physiology of relaxin, the ontogeny of sexual differentiation, diagnostic procedures on the cervix, functional dysmenorrhea and anorexia nervosa, idiopathic edema, and the misunderstood premenstrual tension syndrome.