Part I. Introduction The Institute of Medicine Report, Women's Cardiovascular Health, and Evidence-Based Medicine Nanette K. Wenger Evidence-Based Medicine in the Assessment of Women at Risk for Cardiovascular Disease Leslee J. Shaw Part II. Screening and Diagnosis of Coronary Disease in Women A. Cardiovascular Epidemiology in Women Population-Based Sex Differences in Disease Incidence and Prevalence Brandi J. Witt and Veronique L. Roger Risk Detection and Primary Prevention in Women Lori Mosca and Leslee J. Shaw Early Detection of Coronary Artery Disease in Women: Role of Coronary Artery Calcium Scanning With EBT John A. Rumberger Heart Failure in Women: Epidemiology, Gender Differences in Pathophysiology, and Implications for Therapy Daniel P. Morin, Marvin A. Konstam, Michael E. Mendelsohn, and James E. Udelson Diastolic Dysfunction in Women Mary Norine Walsh and Mariell Jessup Functional Capacity and Activities of Daily Living in Women Claire E. Pothier Snader and Michael S. Lauer Special Considerations for Minority Women Jennifer H. Mieres and Elizabeth Ofili B. Varying Symptom Presentation in Women Clinical Risk Assessment in Women: Chest Discomfort: Report from the WISE Study B. Delia Johnson, Sheryl F. Kelsey, and C. Noel Bairey Merz Quality-of-Life Issues for Women With Coronary Disease John Spertus and Darcy Green-Conaway C. Choosing the Best Diagnostic Test for Women Should All Women With Suspected Coronary Disease Undergo Stress Cardiac Imaging? Anthony P. Morise State-of-the-Art Diagnostic Testing in Women: A Research Update Leslee J. Shaw, B. Delia Johnson, Sharon Mulvagh, Jennifer H. Mieres, Rita F. Redberg, and C. Noel Bairey Merz Part III. Management of Coronary Disease inWomen A. Evaluation of Stable Chest Pain Syndromes in Women Treatment Strategies for Women With Stable Angina, Paul R. Casperson, Leslee J. Shaw, and Robert A. O'Rourke Improving the Diagnosis and Management of Women With Coronary Disease in Primary Care Settings Kimberly J. Rask B. Evaluation of Acute Ischemic Syndromes in Women Evaluation of Acute Chest Pain in Women Andra L. Blomkalns, W. Brian Gibler, and L. Kristin Newby Acute Ischemic Syndromes: Differences in Presentation and Treatment in Women Jane A. Leopold and Alice K. Jacobs C. Variations in Therapeutic Effectiveness in Women Effectiveness of Coronary Revascularization: Gender and Racial Differences Christi Deaton, Cherie L. Kunik, and Eric Peterson Electrophysiology: Treatment Considerations in Women Michael S. Bailey and Anne B. Curtis Exercise Training and Cardiac Rehabilitation for Women Elisa Yuen Man Chiu, Maria Vivina T. Regis, and Erika Sivarajan Froelicher Menopausal Hormone Therapy: Is There Evidence for Cardiac Protection? Nanette K. Wenger Part IV. Economics and Policy Issues in Health Care Related to Women Gender Bias: Is It Real and How Does It Affect Diagnosis, Management, and Outcome? Thomas H. Marwick and Jonathan Chan The Role of Women's Health Centers in Improving Access and Process of Care Susan Kendig and D. Douglas Miller Obstetrician/Gynecologists, Primary Care, and Cardiovascular Disease William W. Hurd, Sheela Barhan, and Robert E. Rogers Health Technology Assessment in the Era of Managed Care: Issues in Women's Health Care Laura Sampietro-Colom, Shawna Jackson, Erin Williams, and Frank J. Papatheofanis Issues in the Analysis of Cost-Effectiveness in the Diagnosis and Treatment of Coronary Artery Disease in Women Adam Atherly and Steven