عنوان

The carbonic anhydrases :

303488446X

3034895704

9783034884464

9783034895705

b554304

The carbonic anhydrases :

[Book]

new horizons

edited by W.R. Chegwidden, N.D. Carter, and Y.H. Edwards.

Basel ; Boston

Birkhäuser

[2000] ©2000

(xviii, 619 pages) : illustrations (some color)

EXS, 90.

Exordium: Remarks on the discovery of carbonic anhydrase --;to the carbonic anhydrases --;Evolution and distribution of the carbonic anhydrase gene families --;An overview of the distribution and function of carbonic anhydrase isozymes in mammals --;The membrane carbonic anhydrases: from CO2transport to tumour markers --;Carbonic anhydrase (CA)-related proteins (CA-RPs), and transmembrane proteins with CA or CA-RP domains --;Regulation of the CA 1, CA 2 and CA 3 genes --;Use of carbonic anhydrase II-deficient mice in uncovering the cellular location of membrane-associated isoforms --;X-ray crystallographic studies of mammalian carbonic anhydrase isozymes --;The catalytic mechanism of mammalian carbonic anhydrases --;Activation of carbonic anhydrase isozymes --;Active-site engineering of carbonic anhydrase and its application to biosensors --;Folding and stability of human carbonic anhydrase II --;Membrane transport and provision of substrates for carbonic anhydrase in vertebrates --;Respiratory and renal roles of carbonic anhydrase in gas exchange and acid-base regulation --;The roles of carbonic anhydrase in metabolism, cell growth and cancer in animals --;The roles of carbonic anhydrase in gustation, olefaction and chemical irritation --;Carbonic anhydrases in striated muscle --;Inherited deficiencies and activity variants of the mammalian carbonic anhydrases --;Carbonic anhydrase inhibition in ophthalmology: Carbonic anhydrase in cornea, lens, retina and lacrimal gland --;Carbonic anhydrase inhibition in ophthalmology: Aqueous humour secretion and development of sulphonamide inhibitors --;The design of new carbonic anhydrase inhibitors --;Roles of carbonic anhydrases in the alimentary tract --;Carbonic anhydrases in the nervous system --;Carbonic anhydrases in calcified tissues --;Carbonic anhydrases of higher plants: an overview --;Plant carbonic anhydrases: structure and mechanism --;Algal carbonic anhydrase --;Bacterial carbonic anhydrases --;Keeping pace with a fast enzyme: steps and missteps --;Carbonic anhydrase research: A clinical perspective, past and future.

Carbonic anhydrase (CA) is a seemingly ubiquitous enzyme of profound physiological importance, which plays essential roles in respiration, acid-base homeostasis, bone resorption, calcification, photosynthesis, several biosynthetic pathways and a variety of processes involving ion, gas and fluid transfer.

Carbonic Anhydrase Inhibitors.

Carbonic anhydrase.

Carbonic Anhydrases.

edited by W.R. Chegwidden, N.D. Carter, and Y.H. Edwards.

N D Carter

W R Chegwidden

Y H Edwards

[Book]

Y