Penetration and Distribution.- Penetration and Distribution of Insecticides.- Metabolism.- Microsomal Oxidation and Insecticide Metabolism.- Cytochrome P450 Interactions.- Extramicrosomal Metabolism of Insecticides.- Enzymatic Conjugation and Insecticide Metabolism.- Target Site Interactions.- The Nervous System: Comparative Physiology and Pharmacology.- Acetylcholinesterase and Its Inhibition.- The Acetylcholine Receptor and Its Interactions with Insecticides.- Effects of Insecticides on Nervous Conduction and Synaptic Transmission.- Insecticides as Inhibitors of Respiration.- Physicochemical Aspects of Insecticidal Action.- Selectivity and Resistance.- The Biochemical and Physiological Basis of Selective Toxicity.- Biochemistry and Physiology of Resistance.- Insecticide Toxicology.- Teratogenic, Mutagenic, and Carcinogenic Effects of Insecticides.- Insecticide Interactions.- The Treatment of Insecticide Poisoning.- Environmental Toxicology.