Genetic Aspects of Disease: Categories of Genetic Disorders --;Biomarkers of Increased Susceptibility to Cancer --;Oncogenes and Tumor Suppressor Genes --;Genetic Factors in Solid Tumors of Childhood --;Retinoblastoma --;Multiple Endocrine Neoplasia --;Hereditary Tumors of the Nervous System --;Hereditary Melanoma and Dysplastic Nevus Syndrome --;Hereditary and Familial Breast Tumors --;Hereditary and Familial Ovarian Cancer --;Genetic Factors in Lung Cancer --;Genetic Factors in Precancerous Lesions and Cancer of the Esophagus --;Genetic Predisposition and Environmental Factors in Gastric Carcinoma --;Hereditary and Familial Colorectal Cancer --;Hereditary Gastrointestinal Polyposis Syndromes --;Familial Aspects in Carcinoma of the Pancreas --;Li-Fraumeni Syndrome --;Genetic Factors in Leukemia and Lymphoma --;Familial Factors in Cancer of the Genitourinary Tract --;Cancer-Prone Hereditary Diseases Associated with Abnormalities of DNA Repair --;Familial Tumors of Other Organs.
From the 1960s onward, the pioneer work of a few investigators clearly showed that hereditary factors were not only related to rare neoplasms, but could also be respon sible for the occurrence of a sizeable fraction of tumors that do not usually show features of inheritance (as in the case of breast or colorectal cancer).