عنوان

Testosterone :

3662008149

9783662008140

b553918

Testosterone :

[Book]

Action · Deficiency · Substitution

edited by Eberhard Nieschlag, Hermann M. Behre.

Berlin, Heidelberg

Springer Berlin Heidelberg

1990

(xi, 285 pages 78 illustrations)

Testosterone: an overview of biosynthesis, transport, metabolism and action --;The role of testosterone in spermatogenesis --;Psychotropic effects of testosterone --;Syndromes caused by androgen resistance --;Pharmacology and clinical use of testosterone --;Comparative pharmacokinetics of androgen preparations: Application of computer analysis and simulation --;Pharmacology of testosterone pellet implants --;Percutaneous dihydrotestosterone (DHT) treatment --;Transdermal testosterone replacement through genital skin --;Safety aspects of androgen therapy --;Effects of androgens on bone metabolism --;Androgens and human benign prostatic hyperplasia (BPH) --;Androgens and carcinoma of the prostate --;Androgens and male senescence.

New developments in testosterone therapy are summarized here by internationally renowned experts. They review both basic and clinical knowledge in fourteen chapters. The book begins with the biochemistry of testosterone, its biosynthesis, metabolism and mechanisms of action in target organs. Three chapters deal with specific aspects of testosterone action, namely its role in spermatogenesis, its psychotropic effects and its effects on bones. Syndromes caused by androgen resistance are described in order to highlight the importance of properly functioning enzymes and receptors in the target organs. Causes and symptoms of male hypogonadism, the major indication for testosterone treatment, are described. Five chapters are devoted to the pharmacology, pharmacokinetics and clinical uses and abuses of testosterone preparations. The new transdermal testosterone application is described in detail. Side effects of testosterone treatment are reviewed. The possible role of androgens in the development of prostatic hypertrophy and carcinoma is discussed extensively since this question is of major concern to the clinician.

Dermatology.

Medicine.

Toxicology.

edited by Eberhard Nieschlag, Hermann M. Behre.

Eberhard Nieschlag

Hermann M Behre

[Book]

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