I The Nature and Presentation of Depression.- 1 Presentation and assessment of depression in old age.- 2 Identification of depression in geriatric medical patients.- 3 The epidemiology and natural history of depression in old age.- 4 Neuroendocrine abnormalities in depression and the influence of drugs.- II Lithium Salts.- 5 Metabolic and endocrine effects of lithium.- 6 Clinical pharmacology of lithium salts.- 7 Lithium in the prophylaxis of depressive illness in late life.- III Tricyclic and Related Antidepressants.- 8 Pharmacokinetics of tricyclic and related antidepressants.- 9 Which antidepressant?.- 10 Cardiovascular effects of tricyclic antidepressants in elderly people.- 11 Side-effects of tricyclic and related antidepressants.- IV Monoamine Oxidase Inhibitor Antidepressants.- 12 Efficacy and problems of MAO inhibitor antidepressants.- V General Management.- 13 Management of acute episodes of depression.- 14 The use of electroconvulsive therapy in elderly depressive patients.- 15 Drug therapy in the management of treatment-resistant depression in elderly people.- 16 Long-term antidepressant treatment in old age.- 17 Factors influencing the outcome of treatment.- Pharmacological and therapeutic agents index.