Aspects of Epidemiology, Pathogenesis and Natural History of Prostatic Cancer.- Oncogenes, Tumour Markers and Monoclonal Antibodies.- The Endocrinological Basis for Hormonal Therapy.- Estrogens and Estramustine Phosphate.- Antiandrogens.- Luteinizing Hormone Releasing Hormone Agonists.- Chemical Adrenal Blockade Treatment.- Total Androgen Blockade.- Second-Line Endocrine Treatment.- Chemotherapy.- The Clinical and Financial Implications of Immediate or Deferred Treatment in Patients with Advanced Prostatic Cancer.- Treatment Recommendations for Daily Practice.