عنوان

Triiodothyronines in Health and Disease

3642815480

9783642815485

b551144

Triiodothyronines in Health and Disease

[Book]

by Inder J. Chopra.

Berlin, Heidelberg

Springer Berlin Heidelberg

1981

(ix, 145 pages 76 illustrations)

Monographs on endocrinology, 18.

1. Description, History, and Calorigenic Activity of Iodothyronines --;2. Transport of Iodothyronines --;A. Thyroxine-Binding Globulin --;B. Thyroxine-Binding Prealbumin --;C. Free Thyroid Hormones --;3. Triiodothyronine: Molecular Structure and Biologic Function --;A. Introduction --;B. Stereochemistry and Molecular Conformation --;C. Conformational Analysis --;D. Role of Iodine in Conformation and Activity --;E. Protein Binding and Biologic Activity --;F. Summary --;4. Concentration of Triiodothyronines (T3 and Reverse T3) in Serum and Other Body Fluids --;A. Methods of Measurements --;B. Serum T3 Concentration in Health and Disease --;C. Urinary Excretion of T3s --;5. Kinetics of Peripheral Metabolism and Production Rates of T3s --;A. Methods of Measurement and Normal Values --;B. Alterations in Thyroid Diseases --;C. Alterations in Nonthyroid Diseases and Low-T3 Syndrome --;6. Sources of T3s: Thyroidal Secretion Versus Extrathyroidal Metabolism of T4 --;7. Nature of the Processes of and Factors Influencing Production of T3s fromT4 --;A. Outer-Ring Monodeiodination of T4 to T3 --;B. Inner-Ring Monodeiodination of T4 to Reverse T3 --;8. Routes of T3s Metabolism --;A. In Vivo Studies --;B. In Vitro Studies --;9. Biologic Effects of lodothyronines --;A. Mechanism of Action --;B. Some Other Interesting Effects of Thyroid Hormones --;C. Relative Potency in Various Effects --;References.

The physiology and metabolism of thyroid hormones were areas of intense research investigation during the 1970s. A list of over 500 references, although probably still incomplete, should lead a reader to at least a few important articles in each area relevant to thyroid hormone physiology.

Endocrinology.

Medicine.

by Inder J. Chopra.

Inder J Chopra

[Book]

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