عنوان

Viral proteins counteracting host defenses

3642594212

9783642594212

b550612

Viral proteins counteracting host defenses

[Book]

edited by U.H. Koszinowski and H. Hengel.

Berlin ; New York

Springer

©2002.

(x, 325 pages) : illustrations

Current topics in microbiology and immunology, 269.

Strategies for the Identification and Analysis of Viral Immune-Evasive Genes --;Cytomegalovirus as an Example / A. Gutermann, A. Bubeck, M. Wagner, U. Reusch, C. Menard, U.H. Koszinowski --;Avoiding Proteasomal Processing: The Case of EBNA1 / N.P. Dantuma, A. Sharipo, M.G. Masucci --;The HCMV Gene Products US2 and US11 Target MHC Class I Molecules for Degradation in the Cytosol / F.J. van der Wal, M. Kikkert, E. Wiertz --;Corking the Bottleneck: The Transporter Associated with Antigen Processing as a Target for Immune Subversion by Viruses / F. Momburg, H. Hengel --;Herpes Viral Proteins Manipulating the Peptide Transporter TAP / E. Reits, A. Griekspoor, J. Neefjes --;Herpes Viral Proteins Blocking the Transporter Associated with Antigen Processing TAP --;From Genes to Function and Structure / D. Bauer, R. Tampe --;Inhibition of the MHC Class II Antigen Presentation Pathway by Human Cytomegalovirus / D.C. Johnson, N.R. Hegde --;Viral Evasion of Natural Killer Cells During Human Cytomegalovirus Infection / V.M. Braud, P. Tomasec, G.W.G. Wilkinson --;Function of CMV-Encoded MHC Class I Homologues / H.E. Farrell, N.J. Davis-Poynter, D.M. Andrews, M.A. Degli-Esposti --;Human Cytomegalovirus Inhibition of Major Histocompatibility Complex Transcription and Interferon Signal Transduction / D.M. Miller, C.M. Cebulla, D.D. Sedmak --;Counteraction of Interferon-Induced Antiviral Responses by Herpes Simplex Viruses / D.A. Leib.

Since the first observations of viral interference with antigen presentation in the MHC class-I pathway, the field has advanced to a detailed analysis. This text discusses proteasomal degradation of an antigenic viral protein, transfer of the proteasomal cleavage products as peptides and more.

Immune response.

Major histocompatibility complex.

Viral proteins.

edited by U.H. Koszinowski and H. Hengel.

H Hengel

U H Koszinowski

[Book]

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