عنوان

Osteoarthritis :

3540651276

9783540651277

b550110

Osteoarthritis :

[Book]

clinical and experimental aspects

J.-Y. Reginster ... With ed. assistance by L. Crasborn.

Berlin ; Heidelberg ; New York ; Barcelona ; Hong Kong ; London ; Milan ; Paris ; Singapore ; Tokyo

Springer, c

1999

XIV, 525 Seiten : Illustrationen, Diagramme ; 24 cm

Literaturangaben.

1 Structure and Function of Normal Human Adult Articular Cartilage.- 2 Epidemiology and Economic Consequences of Osteoarthritis.- 2.1 The American Viewpoint.- 2.2 The European Viewpoint.- 3 Experimental Models of Osteoarthritis.- 3.1 In Vitro Models for the Study of Cartilage Damage and Repair.- 3.2 Animal Models of Osteoarthritis.- 4 Pathophysiology of Osteoarthritis.- 4.1 Role of Mechanical Factors in the Aetiology, Pathogenesis and Progression of Osteoarthritis.- 4.2 Role of Biomechanical Factors.- 4.3 Genetic and Metabolic Aspects.- 4.4 Biochemical Factors in Joint Articular Tissue Degradation in Osteoarthritis.- 4.5 Role of Growth Factors and Cartilage Repair.- 4.6 Role of Crystal Deposition in the Osteoarthritic Joint.- 5 Diagnosis and Monitoring of Osteoarthritis.- 5.1 Direct Visualization of the Cartilage.- 5.2 Radiographic Imaging of Osteoarthritis.- 5.3 Magnetic Resonance Imaging in Osteoarthritis.- 5.4 The Role of Molecular Markers to Monitor Breakdown and Repair.- 6 Evolution and Prognosis of Osteoarthritis.- 7 Impact of Osteoarthritis on Quality of Life.- 8 Medical Management of Osteoarthritis.- 8.1 Medical Aspects.- 8.1.1 Basic Principles in Osteoarthritis Treatment.- 8.1.2 Non-steroidal Anti-inflammatory Drug Administration in the Treatment of Osteoarthritis.- 8.1.3 New and Future Therapies for Osteoarthritis.- 8.2 Regulatory Requirements.- 8.2.1 Preclinical Studies in Osteoarthritis.- 8.2.2 Clinical Evaluation of Drug Therapy.- 9 Surgical Treatment of the Cartilage Injuries.- 10 Scientific Basis of Physical Therapy and Rehabilitation in the Management of Patients with Osteoarthritis.- 11 Conclusion and Perspectives.

Osteoarthritis -- diagnosis.

Osteoarthritis -- physiopathology.

Osteoarthritis -- therapy.

J.-Y. Reginster ... With ed. assistance by L. Crasborn.

J -Y Reginster

L Crasborn

[Book]

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