عنوان

Ganglioside Structure, Function, and Biomedical Potential.

1468412000

9781468412000

b549530

Ganglioside Structure, Function, and Biomedical Potential.

[Book]

Ledeen, Robert W.

Springer Verlag

2013

Plenary Lectures.- Wonders in Glycolipids - A Historical View.- Present Status of the Immunology of Gangliosides.- Use of Cell Cultures in Ganglioside Research.- Structure Analysis and Physical Properties.- Gangliosides: Structure and Analysis.- Structure Analysis of Glycosphingolipids Using Fast Atom Bombardment (FAB) Techniques.- Application of Field Desorption and Secondary Ion Mass Spectrometry for Glycolipid Analysis.- New Techniques for the Investigation of Structure and Metabolism of Sialic Acids.- Recent Advances in Structural Analysis of Gangliosides: Primary and Secondary Structures.- Adrenal Medulla Gangliosides.- Glycosphingolipids of Equine Erythrocytes Membranes: Complete Characterization of a Fucoganglioside.- Physical Behaviour of Glycolipids in Bilayer Membranes: Distribution and Accessibility.- Distribution and Transport.- Ganglioside Distribution at Different Levels of Organization and its Biological Implications.- The Labeling of the Retina and Optic Tectum Gangliosides and Glycoproteins of Chickens in Darkness or Exposed to Light.- Biosynthesis and Transport of Gangliosides in Peripheral Nerve.- Cellular Localization of Gangliosides in the Mouse Cerebellum: Analysis Using Neurological Mutants.- Gangliosides and Related Compounds as Biological Response Modifiers.- Metabolism.- An Outline of Ganglioside Metabolism.- Activator Proteins for the Catabolism of Glycosphingolipids.- Ganglioside Biosynthesis in Rat Liver Golgi Apparatus: Stimulation by Phophatidylglycerol and Inhibition by Tunicamycin.- Incorporation Rate of GM1 Ganglioside Into Mouse Brain Myelin: Effect of Aging and Modification by Hormones and Other Compounds.- Biosynthesis In Vitro of Gangliosides Containing Gg- and Lc-Cores.- Genetic Regulation of GM2(NeuGc) Expression in Liver of Mouse.- New Approaches in the Study of Ganglioside Metabolism.- Mutants and Development.- Glycosphingolipids of Chicken Skeletal Muscle in Early Development and Genetic Dystrophy.- Ganglioside Alterations in the Genetically-Determined Hypertrophic Neuropathy of the Murine Neurological Mutant Trembler.- Comparative and Developmental Behavior of Alkali Labile Gangliosides in the Brain.- Phylogeny and Ontogeny of Vertebrate Brain Gangliosides.- Receptors and Function.- Ganglioside Receptors: A Brief Overview and Introductory Remarks.- Gangliosides as Modulators of the Coupling of Neurotransmitters to Adenylate Cyclase.- Gangliosides, The Thyrotropin Receptor, and Autoimmune Thyroid Disease.- Specific Gangliosides are Receptors for Sendai Virus.- Gangliosides as Receptor Modulators 381.- Brain Gangliosides and Thermal Adaptation in Vertebrates.- Gangliosides and Neurological Diseases.- Gangliosides and Disease: A Review.- Cerebral and Visceral Organ Gangliosides and Related Glycolipids in GM1-Gangliosidosis Type 1, Type 2 and Chronic Type.- Canine GM2-Gangliosidosis : Chemical and Enzymatic Features.- Immunological Expression of Gangliosides in Multiple Sclerosis and in a Demyelinating Model Disease in Rabbits.- Antibodies to Glycosphingolipids in Patients with Multiple Sclerosis and SLE.- Neuritogenesis and Regeneration.- Neuritogenesis and Regeneration in the Nervous System: An Overview of the Problem and on the Promoting Action of Gangliosides.- Effects of Gangliosides on the Functional Recovery of Damaged Brain.- Exogenous Gangliosides Enhance Recovery From CNS Injury.- Ganglioside Induced Surface Activity and Neurite Formation of Neuro-2A Neuroblastoma Cells.- Effect of Exogenous Gangliosides on the Morphology and Biochemistry of Cultured Neurons.- Studies of Gangliosides in Diverse Nerve Cell Cultures.- In-Vitro and In-Vivo Studies on Gangliosides in the Developing and Regenerating Hippocampus of the Rat.- Biomedical Potential of Gangliosides.- Ganglioside Treatment of Genetic and Alloxan-Induced Diabetic Neuropathy.- Double-Blind Controlled Trial of Purified Brain Gangliosides in Amyotrophic Lateral Sclerosis and Experience with Peripheral Neuropathies.- Trials of Ganglioside Therapy for Amyotrophic Lateral Sclerosis and Diabetic Neuropathy.- Treatment of Painful Diabetic Polyneuropathy with Mixed Gangliosides.- Ganglioside (Cronassial) Therapy in Diabetic Neuropathy.- Multicentre Trial on Gangliosides in Diabetic Peripheral Neuropathy.- A Double Blind Placebo Controlled Trial of Mixed Gangliosides in Diabetic Peripheral and Autonomic Neuropathy.- Gangliosides-Clinical Overview.- Participants.- Author Index.

Ledeen, Robert W.

Ledeen, Robert W.

[Book]

Y