عنوان

Clinical Pharmacology of Anti-Epileptic Drugs

3642859216

9783642859212

b548444

Clinical Pharmacology of Anti-Epileptic Drugs

[Book]

edited by H. Schneider, D. Janz, C. Gardner-Thorpe, H. Meinardi, A.L. Sherwin.

Berlin, Heidelberg

Springer Berlin Heidelberg

1975

(xii, 370 pages 129 illustrations)

A. Pharmacokinetics --;Statistical Analysis of Pharmacokinetic Parameters in Epileptic Patients Chronically Treated with Anti-Epileptic Drugs --;Clinical Pharmacokinetics in Monitoring Chronic Medication with AntiEpileptic Drugs --;Drug Interactions at the Metabolic Level: A Reality in Drug Treatment of Epilepsy --;B. Pharmacology of Anti-Epileptic Drugs --;I. Phenytoin --;Comparison of Gas-Chromatographic and Spectrophotometric Determinations of Phenytoin in Serum --;Serum Levels of Phenytoin in Children --;Problems in Controlled Anti-Epileptic Treatment with Phenytoin in Children --;Longitudinal Studies of Serum Anti-Epileptic Drug Levels. Preliminary Observations: Interaction of Phenytoin and Primidone --;Effect of Drug Therapy on the Metabolism of Phenytoin --;II. Ethotoin --;Plasma Concentrations of Ethotoin in Epileptic Patients --;A Gas Chromatographic Method for the Determination of Ethotoin (3- Ethyl-5-Phenylhydantoin) in Human Plasma --;III. Barbiturates --;Some Problems Concerning the Quantitative Assay of Primidone and Its Metabolites --;Determination of Hydroxymetabolites of Phenobarbitone and Phenytoin --;The Effect of Psychotropic Drugs on Serum Anti-Epileptic Levels in Psychiatric Patients with Seizure Disorders --;IV. Carbamazepine --;Carbamazepine: An Attempt to Correlate Serum Levels with Anti-Epileptic and Side Effects --;Pharmacokinetic Data o£ Carbamazepine and its Major Metabolites in Man --;Pharmacokinetic Studies on Carbamezepine in Volunteers and in Epileptic Patients --;A Preliminary Study of Serum Carbamazepine Levels in Healthy Subjects and in Patients with Epilepsy --;Carbamazepine: The Influence of Other Anti-Epileptic Drugs on its Serum Level --;Drug Interaction in Epileptic Patients --;The Influence of Phenobarbitone and Phenytoin on Carbamazepine Serum Levels --;V. Ethosuximide --;Correlation of Serum Ethosuximide Levels with Clinical Effect --;VI. Dipropylacetate --;Less Usual Ways of Administering Anti-Epileptic Drugs --;Enteric Coated Dipropylacetate (Depakine) --;Analytical Data in Connection with the Clinical Use of Di-n-Propylacetate --;VII. Clonazepam --;Clinical Pharmacokinetic Experiences with Clonazepam --;Pharmacokinetics of Clonazepam in Man and Laboratory Animals --;C. Various Aspects (Varia) --;Absorption and Protein Binding in Serum of Several Anti-Epileptic Drugs --;Phenytoin and Phenobarbitone Levels in Human Brain and Cerebrospinal Fluid. --;D. Quality Control and Standardization --;Report on Worksheets Collected after WODADIBOF I --;Results of a Phenytoin Quality Control Scheme --;The Development of a Matrix Reference Standard for Anti-Epileptic Analysis --;E. Methodology of Determination --;Comparison of Methods for Determination of Drugs in Serum and Plasma --;Application of a Nitrogen-Specific Detector for the Gas Chromatographic Determination of Phenytoin, Primidone and Phenobarbitone in 20 [micro]l Serum. --;Consecutive Determination of the Levels of Twelve Anti-Epileptic Drugs in Blood and Cerebrospinal Fluid --;Evaluation of an Experimental Homogeneous Enzyme Immuno-Assay for the Quantitation of Phenytoin and Phenobarbitone in Serum or Plasma --;F. Dictionary of Anti-Epileptic Drug Synonyms, Chemical Names and Nonproprietary Names --;F. Dictionary of Anti-Epileptic Drug Synonyms, Chemical Names and Nonproprietary Names.

epi- lepsy is doing far more than studying epilepsy" Hughlings Jackson Modifying this well-known statement by Jackson, one could say today: "He who is faithfully analysing anti-epileptic drugs is doing far more than studying anti-epileptic drugs".

Medicine.

Pharmacy.

edited by H. Schneider, D. Janz, C. Gardner-Thorpe, H. Meinardi, A.L. Sherwin.

A L Sherwin

C Gardner-Thorpe

D Janz

H Meinardi

H Schneider

[Book]

Y