عنوان

Mechanisms of Cell-Mediated Cytotoxicity II

1468483269

1468483285

9781468483260

9781468483284

b548364

Mechanisms of Cell-Mediated Cytotoxicity II

[Book]

edited by Pierre Henkart, Eric Martz.

Boston, MA

Springer US : Imprint : Springer

1985

Advances in experimental medicine and biology, 187.

I. Non-Lymphocyte Cytotoxic Mechanisms --;Formation Of Protein Channels In Target Membranes --;Ige-Dependent Platelet Cytotoxicity Against Helminths --;Killing of Gram-Negative Bacteria by Neutrophils: Role of 02-Independent System in Intracellular Killing and Evidence Of 02-Dependent Extracellular Killing --;Abberant Oxygen Metabolism in Neoplastic Cells Injured by Cytotoxic Macrophages --;The Cell Biology of Tumor Cell Capture by Activated Macrophages --;Destructive Interactions Between Murine Macrophages, Tumor Cells, and Antibodies of the Igg2A Isotype --;II. Mechanistic Features Shared by CTL and NK Cells --;Reorientation of the Golgi Apparatus and the Microtubule Organizing Center: is it a Means to Polarize Cell-Mediated Cytotoxicity? --;Cytolytic T Cell Granules: Biochemical Properties and Functional Specificity --;The Role of Cytoplasmic Granules in Cytotoxicity by Large Granular Lymphocytes and Cytotoxic T Lymphocytes --;A Unified Theory for the Mechanism of the Lethal Hit by Cytotoxic T Lymphocytes (CTL) and Natural Killer (NK) Cells as Defined by Antisera Capable of Blocking the Lethal Hit Stage of Cytotoxicity --;Human Nk Resistant Tumor Cell Lysis is Effected by IL-2 Activated Killer Cells --;III. NK Cell Mediated Cytotoxicity --;Biochemical Characterization of Natural Killer Cytotoxic Factors --;Both NK Sensitive and Resistant Mycoplasma Free Cell Lines Stimulate Release of NKCF --;Studies of Human Natural Killer Cytotoxic Factor (NKCF): Characterization and Anlaysis of its Mode of Action --;An Investigation of the Role of Soluble Cytotoxic Factors and Reactive Oxygen Intermediates in Lysis by NK Cells --;Analysis of Sequential Substages Of the Natural Killer Cell Lethal Hit --;The Lipoxygenase Pathway in the Human Nk Cell System --;A Serine Proteinase as a "Trigger" For Human Natural Killer Lymphocyte-Mediated Cytolysis --;The Mechanism of Leukoregulin Enhancement of Target Cell Susceptibility to NK Cell Mediated Cytotoxicity in Humans --;IV. The Role of Membrane Components in CTL Function --;Lymphocyte Function-Associated Antigens: Regulation of Lymphocyte Adhesions in Vitro and Immunity in Vivo --;The Function of LFA-1 in Cell-Mediated Killing and Adhesion: Studies on Heritable LFA-1, Mac-1 Deficiency and on Lymphoid Cell Self-Aggregation --;Functional Interactions of LFA-1, T8 and Alloantigen Surface Structures in T-Cell Mediated Cytotoxicity --;Requirement for LYT-2/3 Molecules on Allospecific Cytolytic T Lymphocyte Clones is Dependent Upon Target Cell Antigen Density --;Functional Relationships of LYT-2 and LYT-3 Expression and T Cell Cytototoxicity: A New Model System --;The Role of the T3 Molecular Complex on Human T Lymphocyte-Mediated Cytotoxicity --;The Plasma Membrane 'Skeleton' of Tumor and Lymphoid Cells: a Role in Cell Lysis? --;p215 And p24: Two Membrane-Associated Proteins Expressed on Cloned Cytolytic T-Cells but Not on Cloned Helper T-Cells --;Mechansim of T-Dependent Cytotoxicity: Role of Papain-Sensitive Non CLASS I MHC Target Molecules and Expression of Target Antigen for Cytotoxicity --;Cell Contact Proteins in Antigen-Specific and Antigen-Nonspecific Cellular Cytotoxicity --;V. Post-Binding Events in the Cytotoxic Process --;Evidence for the Molecular Dissociation of Binding and Post-Binding Functions in Cytotoxic Lymphocytes --;Immune Cytolysis Viewed as a Stimulatory Process of the Target --;DNA Fragmentation in Targets of CTL: an Example of Programmed Cell Death in the Immune System --;Mechanism of Rapid Tumor Lysis by Human Adcc: Mediation by Monoclonal Antibodies and Fragmentation of Target Cell DNA --;Cell Surface Thiols, Methylation, and Complementlike Components are Involved in the Early Events of CML Whereas Proteases Participate in the Later, CaDependent Events --;Antigen/Mitogen Induced Cytolytic Activity and IL-2 Secretion in Memory-Like CTL Hybridomas --;Quantitative Models for The Kinetics of Cell-Mediated Cytotoxicity at the Single Cell Level --;Author Index.

This book is derived from contributions to the Second International Workshop on Mechanisms in Cell-Mediated Cytotoxicity, held in Annopolis, Maryland, June 10-13, 1984. The Workshop was a follow-up to the highly successful 1981 Workshop, whose proceedings Workshop were published by Plenum as Mechanisms in Cell-Mediated Cytotoxicity, edited by W.R.

Immunology.

Medicine.

edited by Pierre Henkart, Eric Martz.

Eric Martz

Pierre Henkart

[Book]

Y