pt. I. Basic Molecular Biology. 1. A Historical Perspective on the Clinical Diagnostic Laboratory / Robert E. Moore. 2. An Overview of Nucleic Acid Chemistry, Structure, and Function: The Foundations of Molecular Biology / William B. Coleman. 3. Basic Nucleic Acid Procedures / R. Keith Esch --;pt. II. Molecular Technologies. 4. Nucleic Acid Blotting Techniques: Theory and Practice / Sharon Collins Presnell. 5. DNA Amplification Techniques: An Overview / David H. Sorscher. 6. RT-PCR: Quantitative and Diagnostic PCR in the Analysis of Gene Expression / Robert B. Sisk. 7. PCR-Based Methods for Mutation Detection / Elizabeth M. Rohlfs and W. Edward Highsmith, Jr. 8. Nucleic Acid Hybridization and Amplification In Situ: Principles and Applications in Molecular Pathology / Matthew S. Cowlen. 9. Gene Therapy / Jeffrey S. Bartlett --;pt. III. Applications to Molecular Pathology. 10. An Overview of Molecular Genetics / Gregory J. Tsongalis.
Intended for those in a clinical laboratory with little background in molecular biology who wish to keep up with the growing area of molecular diagnostics. The authors address DNA methods of importance to the clinical laboratorian that highlight applications for the diagnosis of various diseases.
Medical Laboratory Science.
Molecular diagnosis.
Pathology, Molecular.
RB43
.
7
E358
1997
edited by William B. Coleman and Gregory J. Tsongalis.