عنوان

Molecular biology of G-protein-coupled receptors

1468467727

9781468467727

b545706

Molecular biology of G-protein-coupled receptors

[Book]

Mark R. Brann, editor ; foreword by Leslie L. Iversen.

Boston

Birkhäuser

©1992.

(xvi, 326 pages) : illustrations

Applications of molecular genetics to pharmacology.

Rhodopsin / Nicholas J.P. Ryba, Matthew D. Hall and John B.C. Findlay --;Structural, functional, and genetic aspects of receptors coupled to G-proteins / Brian F. O'Dowd [and others] --;Genetic analysis of the [beta]-adrenergic receptor / Catherine D. Strader and Richard A.F. Dixon --;[alpha]-adrenergic receptors: new subtypes, pharmacology, and coupling mechanisms / John W. Regan and Susanna Cotecchia --;5-HT1A receptor: from molecular characteristics to clinical correlates / John R. Raymond, Salah El Mestikawy and Annick Fargin --;Dopamine D1 receptors / Hyman B. Niznik [and others] --;Dopamine D2 receptor / Olivier Civelli [and others] --;Muscarinic acetylcholine receptors / S.V. Penelope [and others] --;Molecular biology of peptide and glycoprotein hormone receptors / David R. Poyner and Michael R. Hanley --;Signal transducing G-proteins: [alpha] subunits --;Immunological probes of the structure, function, and expression of heterotrimeric GTP-binding proteins / Allen M. Spiegel [and others].

It is only in the last two decades that "molecular pharmacology" has blossomed, first with the advent of radioligand binding techniques and second messenger studies which greatly facilitated the biochemical study of drug-receptor interactions, and latterly with increasing knowledge of the molecular architecture of the receptor proteins themselves.

G proteins -- Physiological effect.

G proteins -- Receptors.

Neurotransmitter receptors.

Mark R. Brann, editor ; foreword by Leslie L. Iversen.

Mark R Brann

[Book]

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