Gene Therapy and Tissue Engineering in Orthopaedic and Sports Medicine
[Book]
edited by Johnny Huard, Freddie H. Fu.
Boston, MA
Birkhäuser Boston
2000
(xvi, 286 pages 51 illustrations)
Methods in bioengineering.
I: Background --;1. Gene Therapy in Orthopaedics --;2. The Use of Different Viral Vectors and Strategies for Gene Transfer to the Musculoskeletal System --;II: Gene Therapy Applications for the Musculoskeletal System --;3. Regional Gene Therapy for Hard Tissues --;4. Potential Applications of Gene Therapy to the Treatment of Spinal Disorders --;5. The Development of Approaches Based on Gene Therapy to Improve Muscle Healing Following Injury --;6. Nonviral Gene Therapy: Application in the Repair of Osteochondral Articular Defects --;7. The Potential of Gene Therapy for Osteogenesis Imperfecta --;8. The Role of Nitric Oxide as a Candidate Molecule for Gene Therapy in Sports Injuries --;III: Tissue Engineering in Orthopaedics and Sports Medicine --;9. Stem Cells and Tissue Engineering --;10. Tissue Engineering of Ligament Healing --;11. Muscle-Based Tissue Engineering for Orthopaedic Applications --;12. Application of Tissue Engineering to Cartilage Repair --;IV: Hurdles and Development of New Vectors for Gene Therapy and Tissue Engineering --;13. Immune Reaction Following Cell and Gene Therapy --;14. Vectors for Gene Transfer to Joints --;15. Adeno-Associated Virus (AAV) for Musculoskeletal Gene Transfer.
This book has been written in response to the many physicians and scien- tists working on the development of biological approaches to providing therapies for many orthopaedic disorders as well as to improving the healing of many tissues of the musculoskeletal system.