عنوان

Central nervous system diseases :

0585425299

1592596916

1617371521

9780585425290

9781592596911

9781617371523

b539325

Central nervous system diseases :

[Book]

innovative animal models from lab to clinic

edited by Dwaine F. Emerich, Reginald L. Dean III, Paul R. Sanberg.

Totowa, N.J.

Humana Press

©2000.

(xv, 512 pages) : illustrations

Contemporary neuroscience.

1 --;The Cholinergic Hypothesis a Generation Later: Perspectives Gained on the Use and Integration of Animal Models --;2 --;Patterns of Cognitive Decline in the Aged Rhesus Monkey --;3 --;Cholinergic Lesions as a Model of Alzheimer's Disease: Effects of Nerve Growth Factor --;4 --;The Immunolesioned Animal as a Model of Transmitter Dysfunction --;5 --;An Intracerebral Tumor Necrosis Factor-? Infusion Model for Inflammation in Alzheimer's Disease --;6 --;The Senescence-Accelerated Mouse as a Possible Animal Model of Senile Dementia --;7 --;Transgenic Mice Overexpressing Presenilin cDNAs: Phenotype and Utility in the Modeling of Alzheimer's Disease --;8 --;Intervention Strategies for Degeneration of Dopamine Neurons in Parkinsonism: Optimizing Behavioral Assessment of Outcome --;9 --;Development of Behavioral Outcome Measures for Preclinical Parkinson's Research --;10 --;Behavioral Assessment in the Unilateral Dopamine-Depleted Marmoset --;11 --;Molecules for Neuroprotection and Regeneration in Animal Models of Parkinson's Disease --;12 --;Antisense Knockdown of Dopamine Receptors --;13 --;Is Trophic Factor Gene Disruption a 'Knockout' Model for Parkinson's Disease? --;14 --;Operant Analysis of Striatal Dysfunction --;15 --;Intrastriatal Injections of Quinolinic Acid as a Model for Developing Neuroprotective Strategies in Huntington's Disease --;16 --;Systemic Administration of 3-Nitropropionic Acid: A New Model of Huntington's Disease in Rat --;17 --;Replicating Huntington Disease's Phenotype in Nonhuman Primates --;18 --;Transgenic Mouse Models of Huntington's Disease --;19 --;Rigid Indentation Models of Traumatic Brain Injury in the Rat --;20 --;Rodent Ischemia Models of Embolism and Ligation of the Middle Cerebral Artery: Clinical Relevance to Treatment Strategies of Stroke --;21 --;A Primate Model of Hypertensive Cerebrovascular Disease --;22 --;Nictotinic Therapeutics for Tourette Syndrome and Other Neuropsychiatric Disorders: From Laboratory to Clinic --;23 --;Neural Grafting for Parkinson's and Huntington's Disease --;24 --;Future Prospects of Gene Therapy for Treating CNS Diseases.

Prominent experimentalists critically review the animal models widely used in developing powerful new therapies for central nervous system diseases.

Aging -- physiology.

Alzheimer Disease -- physiopathology.

Central nervous system -- Diseases -- Animal models.

edited by Dwaine F. Emerich, Reginald L. Dean III, Paul R. Sanberg.

Dwaine F Emerich

Paul R Sanberg

Reginald L Dean

[Book]

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