Molecular and Cellular Biology of Insulin-like Growth Factors and Their Receptors
[Book]
edited by Derek LeRoith, Mohan K. Raizada.
Boston, MA
Springer US
1990
Section I: General Aspects of Insulin-Like Growth Factor Physiology --;Somatomedins: A New Look at Old Questions --;Autocrine and Paracrine Effects of the Somatomedins/Insulin-like Growth Factors --;Role of IGFs in Growth Hormone Homeostasis --;Interaction of IGF with the Hypothalamus and Pituitary --;Feedback Regulation of Growth Hormone Gene Expression by Insulin-like Growth Factor I --;Growth Hormone and IGF Abnormalities of the African Pygmy --;Somatomedin Inhibitors --;Section II: Molecular Biology of Insulin-Like Growth Factors --;The Structure and Expression of the Human Insulin-like Growth Factor Genes --;Transcriptional Diversity in Rat Insulin-like Growth Factor I Gene Expression --;Physiological Regulation of Insulin-like Growth Factor Expression --;Dietary and Hormonal Factors Affecting the mRNA Level of IGF-I in Rat Liver In Vivo and in Primary Cultures of Rat Hepatocytes --;Expression of IGF-I in Liver --;Ovarian Insulin-like Growth Factor I: Basic Concepts Leading to Potential Clinical Outlets --;Regulation of Insulin-like Growth Factor-1 Gene Expression by Estrogen --;Regulation of IGF-II Gene Expression in Human Adrenals, Gonads and Placenta --;Expression of Insulin-like Growth Factors by the Human Placenta --;IGFs in Pregnancy: Developmental Expression in Uterus and Mammary Gland and Paracrine Actions during Embryonic and Neonatal Growth --;Hormonal Feedback Regulation of Brain IGF-I and IGF-II Gene Expression --;Expression of the IGF-II Gene in Brain and Muscle --;Regulation of the Neuronal Insulin-like Peptide --;Growth Regulation of Human Breast Cancer by Insulin-like Growth Factors --;Insulin-like Growth Factors in Lung Cancer Cell Lines --;Section III: Structural and Functional Relationships of the Insulin-Like Growth Factor Receptors --;Structural Basis for Ligand-Dependent Transmembrane Signalling of the Insulin and IGF-1 Receptor Kinases --;Identification of the Domains of IGF I Which Interact with the IGF Receptors and Binding Proteins --;Comparison of Insulin-like Growth Factor Receptors in Human Retinal Cells --;IGF I Receptor Phosphorylation --;Regulation of Growth Factor Receptors by Protein Kinase C --;Insulin and Insulin-like Growth Factor I Mediated Phosphorylations in Mouse Neuroblastoma N18 Cells: A Model for Studying Insulin and IGF-I Action on Neural Tissue --;Insulin-like Growth Factor Receptors in the Central Nervous System: Phosphorylation Events and Cellular Mediators of Biological Function --;The Insulin-like Growth Factor-II/Mannose 6-Phosphate Receptor --;The Insulin-like Growth Factor-II/Mannose 6-Phosphate Receptor --;Section IV: Cellular Actions of Insulin-Like Growth Factors --;The Role of Insulin-like Growth Factor Binding Proteins in Controlling the Expression of IGF Actions --;Characterization and Cloning of a Rat Insulin-like Growth Factor Binding Protein --;Neurotrophic Effects and Mechanism of Insulin, Insulin-like Growth Factors, and Nerve Growth Factor in Spinal Cord and Peripheral Neurons --;Insulin-like Growth Factors as Regulatory Peptides in the Adult Rat Brain --;Receptors for Insulin and Insulin-like Growth Factors I and II in pcd Mice and Diabetic Rats Are Unaltered: An Autoradiographic Study --;Insulin-like Growth Factors and Heart Development --;Role of Insulin-like Growth Factor I and II on Skeletal Remodeling --;Effects of Insulin-like Growth Factors on Chromaffin Cells --;Interactions of Insulin and IGFs with Cellular Components of the Arterial Wall: Potential Impact on Atherosclerosis --;Interactions of Insulin-like Growth Factor I (IGF-I) with Multiple Signal Transduction Pathways in FRTL5 Thyroid Follicular Cells --;Contributors.