The Role of Viruses and the Immune System in Diabetes Mellitus :
[Book]
Experimental Models
edited by Thomas Dyrberg.
Berlin, Heidelberg
Springer Berlin Heidelberg
1990
(XI, 139 pages 6 illustrations)
Current topics in microbiology and immunology, 156.
List of Contents --;The Spontaneously Diabetic BB Rat: Sites of the Defects Leading to Autoimmunity and Diabetes Mellitus. A Review --;Immune Pathogenesis of Diabetes in the Nonobese Diabetic Mouse. An Overview --;Streptozotocin Interactions with Pancreatic ß Cells and the Induction of Insulin-Dependent Diabetes --;Autoantigen (64000-Mr) Expression in Coxsackievirus B4-Induced Experimental Diabetes --;Effects of Rubella Virus Infection on Islet Function --;Monoclonal (Auto) Antibodies in Insulin-Dependent Diabetes Mellitus --;The Genetics of Insulin-Dependent Diabetes in the BB Rat --;The Role of Class II Molecules in Development of Insulin-Dependent Diabetes Mellitus in Mice, Rats and Humans --;Major Histocompatibility Complex Molecules and the Beta Cell: Inferences from Transgenic Models.
It is worth noting that while addressing the hypothesis of the role of class II major histocompatibility glycoproteins in autoimmune diabetes (insulin-dependent diabetes, IDDM) a number of investigators established animal models in which class II molecules were expressed under the control of the rat insulin promoter.