THE FUNCTIONAL AND TRANSLATIONAL IMMUNOLOGY OF REGULATORY T CELLS (TREGS),THE ANTI-TUMOR T CELL RESPONSE, AND CANCER; Library of Congress Cataloging-in-Publication Data; Contents; Foreword; Acknowledgments; Introduction; Chapter 1: The Immunobiology and Translational Immunology of Regulatory T Cells; Origin and Importance of Regulatory T Cells; Dual Functional Capabilities; T Cell Regulation and Pregnancy; T Cell Regulation and the Anti-Tumor T Cell Response; T Cell Regulation and Translational Immunology; Intercellular Signaling As a Result of T Cell Receptor Engagement. Translational Events Associated with Thymic Development (Origin) of Innate TregsTranslational Control of Functional Duality in Tregs; Conversion; Reprogramming; Translational Events Associated with Tregs and Pregnancy; Translational Events Associated with Tregs, Dendritic Cells the Anti-tumor T Cell Response; Origin, Types, and Basic Functions of DCs; Interactions between T Cells and DC During the Anti-tumor T Cell Response; Translational Events that Affect DC after Their Interaction with Tregs; Translational Events that Affect Both (Bi-directional) Tregs and DC. Importance of the DC, Treg, and T CellTranslational Events in This Chapter and BeyondChapter 2: Autoimmunity, Tregs, and the Anti-Tumor T Cell Immune System; Immune Cellular Interactions; Autoimmune Responses, Inflammation, and the Induction of Cancer; Translational Pathways Associated with Tregs, Anti-Tumor T Cells, and Cancer Cells in the Autoimmunity/Inflammation Process; Chapter 3: Treg Effector Mechanisms; Introduction; Immune Cellular Interactions; Treg-Only Effector Mechanisms; Translational Pathways Associated with Treg Effector Mechanisms. Chapter 4: Treg Immunobiology as It Relates to the Anti-Tumor T Cell Response during Immune Cell-Based Cancer TreatmentIntroduction; Cellular Interactions; The Importance of Treg Immunobiology As It Relates to the Anti-Tumor T Cell Response during Immune Cell-Based Cancer Treatment; Translational Pathways Associated with Immune Cell-based Immunotherapy; Chapter 5: The Functional and Translational Immunology of Regulatory T Cells (Tregs), the Anti-Tumor T Cell Response, and Cancer: Chapter Review; Chapter 1: The Immunobiology and Translational Immunology of Regulatory T Cells. Chapter 2: Autoimmunity, Tregs, and the Anti-Tumor T Cell Immune SystemChapter 3: Treg Effector Mechanisms; Chapter 4: Treg Immunobiology As It Relates tothe Anti-Tumor T Cell Response during Immune Cell-Based Cancer Treatment; References; Author Contact Information; Index.