1. Autoimmunity and autoimmune diseases like systemic lupus erythematosus -- 2. Overview of cellular immune function in systemic lupus erythematosus -- 3. Etiopathogenesis of systemic lupus erythematosus: the itineraries of three troikas -- 4. MHC class II and non-MHC genes in the pathogenesis of systemic lupus erythematosus -- 5. Genetic susceptibility and class III complement genes -- 6. Complement deficiency and systemic lupus erythematosus -- 7. Gender and age in systemic lupus erythematosus -- 8. Genes and genetics of murine systemic lupus erythematosus -- 9. Systemic lupus erythematosus in domestic animals -- 10. Anti-DNA antibodies: structure, assembly and diversity -- 11. Anticytoplasmic antibodies in SLE: antibodies to cytoplasmic antigens -- 12. Antihistone antibodies -- 13. Antibodis to non-histone agents in systemic lupus erythematosus -- 14. Immune complexes -- 15. Origins of antinuclear antibodies -- 16. The clinical presentation of systemic lupus erythematosus in adults -- 17. Neonatal lupus syndromes -- 18. Systemic lupus erythematosus in childhood -- 19. Imaging of systemic lupus erythematosus: state of the art -- 20. Monitoring patients and systemic lupus erythematosus -- 21. Laboratory evaluation of patients with systemic lupus erythematosus -- 22. Systemic lupus erythematosus pregnancy -- 23. Epidemiology of systemic lupus erythematosus -- 24. Overlap syndromes: mixed connective tissue disease and Sjögren's syndrome -- 25. Systemic lupus erythematosus and fibromyalgia -- 26. Neuropsychiatric systemic lupus erythematosus -- 27. Psychiatric aspects of systemic lupus erythematosus -- 28. Cognitive dysfunction in systemic lupus erythematosus -- 29. Systemic lupus erythematosus and the skin -- 30. Systemic lupus erythematosus and the kidney -- 31. Cardiovascular systemic lupus erythematosus -- 32. Systemic systemic lupus erythematosus and the cardiovascular system: vasculitis -- 33. Systemic lupus erythematosus and the lung -- 34. Nonhepatic gastrointestinal manifestations of systemic lupus erythematosus -- 35. Hepatic disease and systemic lupus erythematosus: coincidence or convergence -- 36. The cellular hematology of systemic lupus erythematosus -- 37. Articular manifestations of systemic lupus erythematosus -- 38. Osteoporosis and metabolic bone disease in systemic lupus erythematosus -- 39. Immunology of antiphospholipid antibodies and co-factors -- 40. The clinical aspects of the antiphospholipid syndrome -- 41. The catastrophic antiphospholipid syndrome -- 42. Hematology: coagulation problems -- 43. The antiphospholipid syndrome: pathogenesis and implications for systemic lupus erythematosus -- 44. Pathophysiology of drug-induced systemic lupus erythematosus -- 45. Drug and environmental systemic lupus erythematosus: clinical manifestations and differences -- 46. Corticosteroid use in systemic lupus erythematosus -- 47. Antimalarials and immunosuppressive therapies -- 48. Unproven and experimental therapies.
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Provides an understanding of the basic mechanisms as well as the diagnostic and therapeutic aspects of lupus. Four-color illustrations throughout, this book is attractive to both the investigative community and clinicians. As lupus has become a paradigm for the study of autoimmune disease, immunologists investigating autoimmunity are becoming more interested in lupus. Basic immunology of phospholipid antibodies, clotting abnormailities, and newest methods of therapy of antiphospholipid syndrome are given in this newest edition of a classic reference.
System requirements: Windows 98 or higher, Pentium processor-based PC, 32 MB RAM (64 MB recommended) 10 MB available hard-disk space, 2x or faster CD-ROM drive, 800x600 resolution VGA monitor supporting thousands of colors (16 bit) or greater, Internet Explorer 5.0 or later or Netscape 4.7 or later.